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The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… analysis of the genomes of nearly 500 papillary thyroid carcinomas (ptc) - the most common form of thyroid cancer - has provided new insights into the roles of …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… the cancer genome atlas (tcga) is a joint effort of the national cancer institute (nci) and the national human genome research … tcga study improves understanding of genetic drivers of thyroid cancer  (2014) rare kidney tumor provides insights on …
News Release
NHGRI researchers have identified new genes associated with the Erdheim-Chester disease (ECD) and some possible new therapies.
… v600e gene mutations, which is sometimes seen in colon cancer , lung cancer , thyroid cancer , brain tumors and some blood cancers . other …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… our aid-as a powerful animal model for research into human cancer . … a genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated … skin cancer and cancer of the colon, rectum, ovary and thyroid . coauthors of the paper in the march 12, 2015, …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… is a leader in the application of genome science to cancer research. his recent studies investigate the genetic … asian hepatocellular carcinoma and cholangiocarcinoma . cancer cell , 32(1):57-70.e3. 2017. killian jk, dorssers lc, … ps, hager gl, cheng sy. transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor …
News Release
NIH researchers have created a data resource show how differences in an individual's genome can affect gene activity and contribute to disease.
… tissues, and can predispose people to diseases such as cancer , heart disease and diabetes. "gtex was designed to … institute of mental health (nimh) and the national cancer institute (nci), all part of nih. "gtex will be a … tissue types: fat, heart, lung, skeletal muscle, skin, thyroid , blood, and tibial artery and nerve. the genomic …
Staff
Dr. Teri Manolio is the director of the Division of Genomic Medicine at the National Human Genome Research Institute. ​
… mosaicism from birth to old age and its relationship to cancer . nature genetics , 44:642-50. 2012. [ pubmed ] … near foxe1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for … la, gillanders em, manolio ta. genetic architecture of cancer and other complex diseases: lessons learned and future …