Search Results
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… to a pattern of DNA sequences that appears frequently in bacterial DNA. Scientists believe the CRISPR sequences …
The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… of a modified viral vector or a linear fragment of bacterial DNA. After the artificial DNA is inserted, the …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
Staff
Dr. Sergey Koren is an associate Investigator in the Genome Informatics Section of the Center for Genomics and Data Science Research.
… for high-quality assembly. This work has revolutionized bacterial genome assembly, giving complete and accurate …
For Teachers
Lesson plan based on an award-winning DNA from the Beginning website, an animated primer on the basics of DNA, genes and heredity.
… PROBLEM section: When the F factor is integrated into the bacterial chromosome, can it still act as a donor in a …
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
… typically involves propagating the recombinant DNA in a bacterial or yeast cell, whose cellular machinery copies the …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
… the environment, or national security. The first synthetic bacterial genome was completed in 2008 with the synthesis of …
News Release
NHGRI hosted a CRISPR "Ask Me Anything" with Jennifer Doudna, Ph.D., reaching 10.5 million people worldwide.
… trials would include using Cas9 proteins from different bacterial species, which humans bodies have never seen. This …
Fact Sheet
Genomic research has been central to understanding and combating the SARS-CoV-2 (COVID-19) pandemic.