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Talking Glossary
El cáncer es una enfermedad en la que algunas células del cuerpo crecen fuera de control. Hay muchos tipos diferentes de cáncer, y cada uno comienza cuando una única célula adquiere un cambio genómico (o mutación) que le permite dividirse y multiplicarse sin control.
… que le permite dividirse y multiplicarse sin control. … Cancer is a disease in which some of the body’s cells grow uncontrollably. There are many different types of cancer, and each begins when a single cell acquires a genomic … and multiply unchecked. Additional mutations can cause the cancer to spread to other sites. Such mutations can be caused …
Genetic Disorders
Colon cancer is a malignant tumor of the large intestine that affects both men and women.
… Colon cancer, a malignant tumor of the large intestine, affects … States, approximately 160,000 new cases of colorectal cancer are diagnosed each year. … Colon cancer, a malignant tumor of the large intestine, affects …
News Release
SJS/TEN is a severe drug reactions that affect the skin, and one of the most severe of adverse reactions affecting any system in the body
… Necrolysis (SJS/TEN). SJS/TEN is the severest of adverse drug reactions that affect the skin, and one of the most … organized a workshop , in collaboration with the Food and Drug Administration (FDA) and other NIH institutes, to … factors that predispose patients to severe immune mediated drug reactions like SJS/TEN, as well as studying the …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from skin cancer. One in 6 American men will develop prostate cancer …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… Bruce Agnew … For many cancer patients and their doctors, the deadliest enemy is metastasis - the migration of cancer cells from the original tumor to other places in the … Such high-throughput screening has identified thousands of drug candidates over the past 10 years but has resulted in …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Kyle Davis … Receiving a cancer diagnosis can feel like losing control of everything. … its natural defenses, which can then lead to diseases like cancer," said Laura Elnitski, Ph.D., a senior investigator in … chance of survival. But the same isn't true for prostate cancer, where it can indicate more aggressive cancers. Thus, …
For Patients and Families
​Pharmacogenomics combines the science of how drugs work, called pharmacology, with the science of the human genome, called genomics.​
… genetic makeup, or genome, to choose the drugs and drug doses that are likely to work best for that particular … to better ways of using drugs to manage heart disease, cancer, asthma, depression and many other common diseases. … a bad reaction to the drug. Another example is the breast cancer drug trastuzumab (Herceptin). This therapy works only …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated … to combat BRAF -associated cancers and seeking ways around drug resistance. Moreover, "because of the very high …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no detectable cancer. But, unfortunately, some patients will hear the word …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… Steven Benowitz … An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because … Canine transmissible venereal tumor, or CTVT, spreads when cancer cells move from one dog to the other during sexual … immune systems from detecting and fending off invading cancer cells. They reported their results online July 31, …