Search Results
Staff
Dr. Wilson is the co-chief of and senior investigator in NHGRI's Computational and Statistical Genomics Branch.
… properties of newly developed methods of genetic analysis for quantitative traits. … The overarching goal of … linear regression framework that can be applied to family data and have been designed for data with very large numbers of genetic markers (millions), …
Research Funding
GS-IT provides sequence analysis tools and software to scientists who rely on genomics in their research.
… GS-IT is intended to democratize access to useful analysis software for these researchers. The GS-IT strategy … who are seeking tools they can successfully use for analysis. The iSeqTools Portal developed under GS-IT … Tools (GS-IT) provides "researcher friendly" sequence analysis tools and software to a broad community of …
Research at NHGRI
The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence.
… genomics facility that emphasizes the generation and analysis of DNA sequence. In addition to providing … applications, with a goal not simply to produce sequence data, but to produce the infrastructure required to bring … Program to develop novel methods to analyze genomics data with applicability to clinical and basic science …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… samples from 33 cancer types. The over 2.5 petabytes of data generated through TCGA remain publicly available for … community to use. … NIH completes in-depth genomic analysis of 33 cancer types (2018) The Cancer Genome Atlas … The Cancer Genome Atlas completes detailed ovarian cancer analysis (2011) Researchers discover key mutation in acute …
Policy Issues
Most genetic tests today are not regulated, meaning that they go to market without any independent analysis to verify the claims of the seller.
… meaning that they go to market without any independent analysis to verify the claims of the seller. … Several … but typically, health care insurers like CMS draw on data from the research and medical communities to determine … made false or misleading claims about its privacy or data security procedures or failed to employ reasonable …
News Release
NHGRI will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases.
… of Health will fund a set of genome sequencing and analysis centers whose research will focus on understanding … among the program grantees, and to contribute to data analysis and program outreach. In addition, the National … this group will play a key scientific role by improving data availability and leading various data analyses efforts. …
News Release
eMERGE Network will support multiple clinical sites and a coordinating center with $75 million over five years.
… as age, body-mass index, alcohol use and other clinical data, all of which can affect an individual’s risk for … aim to investigate ways to incorporate additional clinical data into the risk score calculations. Researchers have … Network will also leverage the NHGRI Genomic Data Science Analysis, Visualization, Informatics Lab-space (AnVIL) …
The Genomics Landscape
In the August 4, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about the establishment of the Global Biodata Coalition (GBC), which aims to move towards more internationally coordinated, sustainable, and streamlined mechanisms that support the biodata ecosystem.
… Human Genome Project (HGP) was to submit their sequence data into a public database within 24 hours of being … to as the “Bermuda Principles.” The legacy of rapid data sharing within the HGP, as well as other large … genomics projects, remains today. Open, quick, and quality data sharing—though not without its challenges—is an ideal …
Event
Joint workshop featuring overviews of Roadmap Epigenomics and ENCODE resources that are freely available for use by the research community.
… practical experience with searching and downloading data from the ENCODE Portal, querying ENCODE data using the ENCODE Element Browser, exploring genome-scale chromatin interaction data using the 3D Genome Browser, and using the WashU …
NEWS RELEASE
Final outcomes from the most comprehensive analysis to-date of humans and their microbiomes definitively link microbes and microbial activities with health problems.
… Ph.D. … Final outcomes from the most comprehensive analysis to-date of humans and their microbiomes definitively … births and 90 full-term births. By looking at microbiome data, as well as other features, including gene expression, … metabolites and other biological properties. With that data, researchers were able to study the interplay of the …