Search Results
Healthcare Provider Genomics Education Resource
Genomics plays a role in every area of nursing, whether nurses are at the bedside providing one-on-one care, treating entire populations, teaching the next generation of nurses, or making discoveries in the lab.
… scale changes such as duplications or deletions. Gene expression tests analyze mRNA and can identify over- or under-expression of certain genes, which affects what proteins are …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
Event
On November 1-5, 2023, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.  The annual meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of human genetics.Â
… M Buckley eQTL analysis of canine testes identifies gene expression patterns associated with canine body size. PB1092 … Sequencing to Fine-Map an Alloimmunization Susceptibility Locus in Sickle Cell Disease PB3447 Vence Bonham …
Staff
Dr. Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… and transcriptomic technologies alongside population and quantitative genetics to identify the genes and gene-pathways … in the response to red blood cell transfusions and the expression of beta-globin genes.   … We are a part of a … Disease Reveals African-Ancestry-Limited Association at a locus on Chromosome 5. Blood Adv. 2018 Dec 26;2(24):3637-364; …
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
… H, Charles BA, Christman MF, Rotimi CN. UGT1A1 is a major locus influencing bilirubin levels in African Americans. Eur … Y, Oli J, Johnson T. Genomewide scan and fine mapping of quantitative trait loci for intraocular pressure on 5q and 14q in West …
Staff
Elaine Ostrander is chief of NHGRI's Cancer Genetics and Comparative Genomics Branch.
… in humans often fail due to sample size limitations and locus heterogeneity; factors the Ostrander lab argues can … metastatic lethal variants and included gene expression studies 46, 47 , 48 , 49 , 50 , 51 . … We have, … Carvunis AR, Bannasch DL, Ostrander EA, Ideker T. (2020) Quantitative translation of dog-to-human aging by conserved …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… to engineer megabase changes to mammalian genomes in a locus-agnostic manner and v) Develop imaging technology to … require accurate manipulation of DNA sequences and gene expression as well as interrogation of the functional … entire field of epitranscriptomics research: a dearth of quantitative sequencing methods that can comprehensively map …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
Staff
Dr. Meru Sadhu is the head of the Systems Biology and Genome Engineering Section at the National Human Genome Research Institute. ​
… Kruglyak L. Rare variants contribute disproportionately to quantitative trait variation in yeast. eLife . 24;8:e49212. doi: … for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast . Nat Genet . …
News Release
Six new grants will support researchers for new computational approaches to search millions of genomic variants for disease susceptibility.