Search Results
Educational Resources
LOD stands for "logarithm of the odds." In genetics, the LOD score is a statistical estimate of whether two genes, or a gene and a disease gene, are likely to be located near each other on a chromosome.
… score is a statistical estimate of whether two genes, or a gene and a disease gene, are likely to be located near each other on a … probability that two loci (e.g., a disease-associated gene and another sequence of interest, such as a variant or …
News Release
When it comes to Attention-Deficit/Hyperactivity Disorder (ADHD), genetics do make an impact.
… unlike some illnesses, which are determined by a single gene, ADHD is not easily pinned down. Many common but subtle …
News Release
CMG investigators have made significant inroads in discovering genes underlying Mendelian conditions and have uncovered 470 new, previously unknown conditions.
… inherited, and typically caused by a mutation in a single gene. So far, researchers have identified the genomic causes … the program's progress and the breadth of Mendelian gene discovery to date. The authors also ruminated on the … disease. "Knowing that there is a relationship between a gene and a disease has enabled us to probe the development …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… the cell's machinery know when to activate or inactivate a gene. In healthy cells, these flags are correctly placed and … chemical groups, which act like on/off switches for a gene, are incorrectly added to many places on the cell's DNA. … control of everything. … cancer, cancer diagnosis, cancer therapy, genome sequencing, Precision medicine, epigenome, …
News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… to identify and characterize their functional roles in gene regulation. "A key challenge in ENCODE is that … to turn genes on or off, or tune the exact levels of gene activity, help drive the formation of distinct cell … has benefited from and built upon decades of research on gene regulation performed by independent researchers around …
Talking Glossary
LOH (short for “loss of heterozygosity”) refers to a type of mutation that results in the loss of one copy of a segment of DNA (typically containing a gene or group of genes).
… of one copy of a segment of DNA (typically containing a gene or group of genes). … LOH (short for “loss of … of one copy of a segment of DNA (typically containing a gene or group of genes). For most parts of the genome, human … of one copy of a segment of DNA (typically containing a gene or group of genes). … Talking Glossary …
Educational Resources
Antisense is the non-coding DNA strand of a gene.
… Antisense … Antisense is the non-coding DNA strand of a gene. … Non-coding DNA, Messenger RNA, Protein Synthesis … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template for … a protein. … Antisense is the non-coding DNA strand of a gene. … Educational Resources …
News Release
Researchers are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall.
… overall. … Precision medicine, drug prescribing, drug therapy, Vence Bonham, longitudinal drug studies, drug …
Educational Resources
Genomic variation refers to diversity in gene frequencies.
… Variation … Genomic variation refers to diversity in gene frequencies. … Genetic Variation, Genetic Testing, … effects. … Genomic variation refers to diversity in gene frequencies. … Educational Resources …
Educational Resources
Dominant refers to the relationship between two versions of a gene.
… refers to the relationship between two versions of a gene. … Dominant, Recessive, Alleles, Family Health History, … refers to the relationship between two versions of a gene. Individuals receive two versions of each gene, known as alleles, from each parent. If the alleles of a …