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News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… to identify and characterize their functional roles in gene regulation. "A key challenge in ENCODE is that … to turn genes on or off, or tune the exact levels of gene activity, help drive the formation of distinct cell … marks, and new data types, such as long-range DNA interactions and protein-RNA interactions." As a new feature, …
Staff
Dr. Sharon Milgram is an adjunct investigator in the Genetics and Molecular Biology Branch at the National Human Genome Research Institute.
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… Other metabolic pathways actually help to build molecules. Gene-regulation pathways turn genes on and off. Such action … a certain product or a change in the cell. … Biochemistry, Gene Expression, Metabolism, Medication … A biological …
News Release
The NHGRI Short Course in Genomics brings the latest genomics science to the classroom.
… topics, including genome sequencing, CRISPR and other gene-editing methods, the human microbiome, and ethical and … Lassar said. "Even though we missed out on the casual interactions of an in-person experience, we were able to have …
Event
The Advances in Genomic Technology Development (AGTD) 2023 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) in-person and virtually from Tuesday, June 6, until Thursday, June 8, at The Sanford Consortium for Regenerative Medicine, La Jolla, CA.
… Morris, Ph.D. NHGRI Genome Technologies: Protein-DNA Interactions Session Moderators: Michal Rozenwald, University … 8:45 a.m. STAMPing RNA binding protein-RNA networks Gene Yeo, Ph.D., MBA University of California, San Diego … Hugo Medina-Muñoz, Ph.D., UC, San Diego presents: Gene Yeo, Ph.D., MBA, University of California, San Diego and …
Healthcare Provider Genomics Education Resource
Genomics plays a role in every area of nursing, whether nurses are at the bedside providing one-on-one care, treating entire populations, teaching the next generation of nurses, or making discoveries in the lab.
… whole person and consider the influence of biopsychosocial interactions on health outcomes.  Care for patients of all … health and illness that is influenced by genomics and the environment.  Obtain a family history to assist with early …
Event
On March 12-16, 2024, the National Human Genome Research Institute (NHGRI) will participate in the 2024 ACMG Annual Clinical Genetics Meeting - an annual medical and scientific conference continues to provide groundbreaking research and the latest advances in medical genetics, genomics and personalized medicine.
… Tractography Correlate with Clinical Outcomes Following Gene Therapy for GM1 Gangliosidosis: New Biomarker for … P474 Secondary Findings Analysis in the Personalized Environment and Genes Study: Reduced Return in Disorders with …
Research Funding
Frequently Asked Questions for IGVF RFAs: RFA-HG-20-043, RFA-HG-20-044, RFA-HG-20-045, RFA-HG-20-046, RFA-HG-20-047
… Although perturbations such as a drug, hormone, or gene knockout may be allowable, these should be used to map … are primarily focused on generation of a resource of gene and regulatory maps while Regulatory Network Projects … network projects should not be dependent upon such interactions. Is spatial data essential for the Networks RFA? …
Research Funding
The three research domains to be considered for support by the NHGRI Ethical, Legal and Social Implications Research Program.
… the interplay among genetic factors, the physical environment and the social environment, and how this … How individuals, families and communities understand the interactions between genetic, social and environmental … on provider and patient uptake of genomic healthcare and gene therapy. Impacts of the results of genomic and genetic …
Profile
Dr. Pavan looks back on his career at NHGRI, highlights pivotal moments and shares his future plans in artistic woodworking and community mediation.
… in a highly interactive, collaborative, and supportive environment. I had high risk projects that were supported so … transformative discoveries are made.  We would identify a gene from a screen or from observing a trait in an animal model, and then we explored what that gene did. That would often take us into a system or field …