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The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … which tumors are more aggressive and which are more likely to respond to certain treatments. Their findings confirmed … about NIH and its programs, visit http://www.nih.gov . … Related Content … TCGA study improves understanding of …
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The gene is the basic physical unit of inheritance.
… … The gene is considered the basic unit of inheritance. Genes are passed from parents to offspring and contain the information needed to specify physical and biological traits. Most genes code for specific proteins, or segments of proteins, …
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A candidate gene is a gene whose chromosomal location is associated with a particular disease or other phenotype.
… associated with a particular disease or other phenotype. … Genes, Chromosome, Phenotype, Traits, Disease, Linkage Analysis … The term candidate gene refers to a gene that is believed to be related to a particular trait, such as a disease or a …
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Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Mutations affecting the RTK/RAS/RAF pathway can cause it to become stuck in the "on" state. As a result, signals that … activity in 62 percent of the samples. The affected genes are oncogenes, or genes that have the potential to … of lung cancer comprise the most common cause of cancer-related deaths worldwide, with more than 1 million deaths …
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How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… Jeannine Mjoseth … How well cancer patients fare after chemotherapy can be affected by … with other patients during treatment, according to a new study by researchers at the National Human Genome … the difference occurred, but hypothesize that it may be related to stress response. "When you're stressed, stress …
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A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… Jeannine Mjoseth … A repurposed cancer drug appears to reduce the severity of lesions and … that accompany the disease." … Encouraging Results … Related Content … Cancer drug reduces pain, improves symptoms …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… large numbers of genotypes (an individual's collection of genes). Until now, it has been difficult for researchers to re-contact individuals with genotypes of interest and … about NIH and its programs, visit www.nih.gov . … Related Content … NIH pilot project will match researchers to …
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Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
… of a trait that results from the interplay between genes and the environment. … Genes, Environmental Factors, Genetics, DNA … Gene–environment interaction refers to the interplay of genes (and, more broadly, genome …
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Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… … Genetic Disease, Genetic Disorder, Gene Mutation, Cancer Treatment, Healthcare … Gene therapy is a technique that uses a gene(s) to treat, prevent or cure a disease or medical disorder. …
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A gene pool is the total genetic diversity found within a population or a species.
… within a population or a species. … Genetic Diversity, Genes, Extinction, Population Genetics … A gene pool refers to the combination of all the genes (including alleles) present in a reproducing population …