Search Results
Media Availability
Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… Researchers have created a promising new method to accurately and, in some cases, more comprehensively … exome, the portion of the genome where many key cancer-related genes are located. Initially, they showed that two different …
Fact Sheets
Un ratón con genes desactivados es un ratón de laboratorio en el que los investigadores han desactivado, o "noqueado", un gen existente. ​
… Un ratón con genes desactivados [en inglés, conocidos como "ratones … y fÃsicas observables. … ¿Para qué se usan los ratones con genes desactivados? Dejar fuera la actividad de un gen ofrece … ese gen hace normalmente. Los seres humanos tienen muchos genes en común con los ratones. Por consiguiente, observar …
Research at NHGRI
The Democratizing Education for Sickle Cell Disease Gene Therapy project utilizes a deliberative stakeholder-engagement approach to develop patient educational materials for sickle cell disease gene therapy.
… so they can make an informed decision on whether to participate. Patients need accessible, understandable, and actionable educational materials to help them make such decisions. … The Democratizing … therapy resources. Please email your comments or questions to DemocratizingEd@mail.nih.gov . These educational materials …
Research Training
Competitive scholarships for students from disadvantaged backgrounds to support careers in biomedical, behavioral and social science health-related research.
… Scholarship Program (UGSP) offers competitive scholarships to students from disadvantaged backgrounds that are committed … in biomedical, behavioral, and social science health-related research. … The UGSP offers scholarship support, paid … in biomedical, behavioral and social science health-related research. … NIH Undergraduate Scholarship Program, …
Educational Resources
X-linked, as related to genetics, refers to characteristics or traits that are influenced by genes on the X chromosome.
… X-Linked … X-linked, as related to genetics, refers to characteristics or traits that are influenced by genes on the X chromosome. … Chromosome, Mutation, Sex …
News Release
NIH is launching a program, Molecular Phenotypes of Null Alleles in Cells (MorPhiC), to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.
… Alleles in Cells program will first look at protein-coding genes … The National Institutes of Health is launching a program to better understand the function of every human gene and …  Danwei Huangfu, Ph.D. Sloan-Kettering Institute for Cancer Research, New York City Center for scalable knockout …
Genetic Disorders
WAGR syndrome is a genetic condition caused by a deletion of genes located on chromosome 11, often causing eye problems and increased risk of cancer in babies.
… rare genetic condition caused by a deletion of a group of genes located on chromosome number 11. Babies born with WAGR … located on chromosome number 11 (11p13 - the "p13" refers to the specific place on chromosome 11 that is affected). … rate of patients with Wilms tumor is excellent and is related to the features of the tumor, and the stage of the …
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… group is essential in providing resources and services related to genomic research for NHGRI investigators. As head of the … Unit, his research efforts led to the identification of genes, and exploring the biological functions of the encoded …
News Release
NIH researchers have identified a gene that makes yeast resistant to a lethal toxin.
… yeast cells. The neighboring cells here are very sensitive to the toxin, creating a large zone around the colony where … yeast cells. The neighboring cells here are very sensitive to the toxin, creating a large zone around the colony where … of resistant versus sensitive yeast to identify which genes confer resistance to the toxin.  Through this …
Fact Sheet
Today, gene therapy for sickle cell disease is considered experimental and only available to you if you participate in a clinical trial.
… participation in a clinical trial  If you are referred to a certain trial, you should learn about: Phases of a … worked.  … Step 2: Eligibility  Your eligibility to participate in a trial may be dependent on: Your age. Your diagnosis of sickle cell disease. Your response to other treatments. Whether you are taking any other …