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Staff
Dr. Sharon Milgram is an adjunct investigator in the Genetics and Molecular Biology Branch at the National Human Genome Research Institute.
… cell signaling and protein trafficking in polarized cells, including kidney and airway epithelial cells. Epithelial cells form a lining at the surface of the skin and along …
Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
News Release
National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration. The study may inform the development of treatments for hearing loss in humans.
… Ph.D., NHGRI. … Confocal image of adult zebrafish hair cells (green) in the auditory organ of the inner ear. Credit: … come from the loss of hearing receptors known as “hair cells” in the inner ear. Bristles that stick out of these microscopic hair cells move and bend when sound travels into our ears, …
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … Cloning, Bacteria, … DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). BACs are often used in … with their inserted DNA, are then taken up by bacterial cells. As the bacterial cells grow and divide, they amplify …
Talking Glossary
Aneuploidy is an abnormality in the number of chromosomes in a cell due to loss or duplication. In humans, aneuploidy would be any number of chromosomes other than the usual 46.
Staff
Dr. Edward Giniger is an adjunct investigator in NHGRI's Genetics and Molecular Biology Branch.
… to find just the right partners from among all the myriad cells of the nervous system. His laboratory also seeks to … shown how a particular protein on the surface of fly nerve cells, called Notch, engages signaling proteins inside the … information processing, neural circuits, neurons, nerve cells … Edward Giniger, information processing, neural …
News Release
NIH is launching a program, Molecular Phenotypes of Null Alleles in Cells (MorPhiC), to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.
… The Molecular Phenotypes of Null Alleles in Cells program will first look at protein-coding genes … The … each gene. The Molecular Phenotypes of Null Alleles in Cells (MorPhiC) program, managed by the National Human Genome … or off depending on the cell’s relationship to surrounding cells, environment and age. Research funded by the MorPhiC …
Event
Pre-application webinar on for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) data analysis validation centers funding opportunity announcement (FOA) on September 7, 2022.
… Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase I: Data Analysis and Validation Centers … webinar on for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) data analysis validation centers funding … webinar on for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) data analysis validation centers funding …
News Release
NIH researchers researchers and collaborators have gained some key insights into the biological inner-workings of regrowing a body, the evolution of aging and a unique method to dispose of aging cells, by studying the genomes of a hermit crab (Hydractinia symbiolongicarpus).
… and corals regrows its entire body with help from “aging” cells. … Insights into healing and aging were discovered by … and age-related diseases. Typically, in humans, senescent cells stay senescent, and these cells cause chronic inflammation and induce aging in adjacent …
Educational Resources
DNA replication is the process by which a molecule of DNA is duplicated.
… is the process by which the genome’s DNA is copied in cells. Before a cell divides, it must first copy (or …