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News Release
The goat has contributed its DNA to a new method for high-quality, low-cost genome reconstruction, one that will be useful for reading human and other genomes.
… its DNA to a study that presents a new method for high-quality, low-cost genome reconstruction. In addition to … contributed DNA to a study that presents a new method for high-quality, low-cost genome reconstruction. Credit: Brian L … research. "Now that we've proven these methods produce high-quality genome reconstructions, they can be applied to …
Staff
Dr. James Inglese is an adjunct investigator in NHGRI's Metabolic Medicine Branch.
… and international chemical biology consortia. … High throughput technologies enable assays of biochemical, … an experimentally efficient and reproducible manner. These high throughput screening, or HTS, assays enable the … in NHGRI's Metabolic Medicine Branch. … James Inglese, high-throughput screening, large synthetic compound …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… Types of treatments A variety of approaches target the blood stem cells to reduce your symptoms of sickle cell … aim to decrease the amount of hemoglobin S in your red blood cells. If they successfully decrease the hemoglobin S, … the severity of the disease. Learn more about your red blood cells to help you better understand these various …
Staff
Dr. Douglas Stewart is an associate investigator in NHGRI's Center for Precision Health Research.
… disorder. Dr. Stewart is leading a project which uses new high-throughput sequencing technologies to identify, catalog … tumor-predisposition disorders, neurofibromatosis, high-throughput sequencing technologies … Dr. Douglas Stewart …
Fact Sheets
Among the 24 chromosomes that make up the human genome, the Y chromosome is unique for its highly repetitive structure. Scientists are studying the Y and its unusual features to better understand human health and disease.
Media Advisory
With the publication of 16 high-quality reference genomes from across vertebrates, the Vertebrate Genome Project establishes standards for biodiversity genomics and reports discoveries in comparative biology, conservation, and health research
… the echidna and the platypus. With the publication of 16 high quality reference genomes from across vertebrates, the … methods such as better long-read sequencing to achieve high-quality near-complete genomes for the nearly 71,000 … 16 animal reference genomes … With the publication of 16 high-quality reference genomes from across vertebrates, the …
Talking Glossary
GMO (short for “genetically modified organism”) is a plant, animal or microbe in which one or more changes have been made to the genome, typically using high-tech genetic engineering, in an attempt to alter the characteristics of an organism.
… more changes have been made to the genome, typically using high-tech genetic engineering, in an attempt to alter the … more changes have been made to the genome, typically using high-tech genetic engineering, in an attempt to alter the … more changes have been made to the genome, typically using high-tech genetic engineering, in an attempt to alter the …
News Release
Researchers have released a new high-quality collection of reference human genome sequences that captures substantially more diversity from different human populations than what was previously available.
… Darryl Leja, NHGRI. … Researchers have released a new high-quality collection of reference human genome sequences … “pangenome” reference … Researchers have released a new high-quality collection of reference human genome sequences … previously available. … Researchers have released a new high-quality collection of reference human genome sequences …
Staff
Dr. James Thomas is the acting director for the NIH Intramural Sequencing Center (NISC).
… … James Thomas, NIH Intramural Sequencing Center (NISC), high-throughput sequencing, comparative genomics, data …
News Release
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
… identification of genomic variants associated with blood lipid levels. … In a large-scale study of people from … of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to … Lipids are fat-like substances that can be found in blood and body tissues. They come in two major forms — …