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Fact Sheets
A DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes.
… related to those drugs.With the advent of new DNA sequencing technologies, some of the tests for which microarrays were used in the past now use DNA sequencing instead. But microarray tests still tend to be …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… and the field of genomics. … The NIH Intramural Sequencing Center (NISC) sits on the top floor of a research … unassuming location houses the Center's state-of-the-art, high-throughput DNA sequencing facility. In a rather modest start …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… and National Cancer Institute Deputy Director for Advanced Technologies and Strategic Partnerships Anna D. Barker find … genome analysis technologies, including large-scale genome sequencing. … The Cancer Genome Atlas … The Cancer Genome … genome analysis technologies, including large-scale genome sequencing. … Effort to accelerate understanding of the …
News Release
Jeffery Schloss, Ph.D., Division of Genome Sciences director, was honored with the HHS Career Achievement Award for his work in genome sequencing technology.
… (HHS) Career Achievement Award for his work in genome sequencing technology. HHS Secretary Sylvia Mathews Burwell … Research Program that aim to develop DNA analysis technologies," said Eric Green, M.D., Ph.D., NHGRI director. … costs by nearly a million-fold." "Bringing the cost of high-quality human genome sequencing down to $1,000 or less …
Infographic
An infographic that explains why it was so difficult to fully complete the human genome sequence.
… Over the past two decades, researchers developed new technologies to read longer stretches of DNA - from only … genome sequence until new laboratory and computational technologies were developed. It took almost twice as long to … with a vision. Even with new technologies, genome sequencing is still tough, time-consuming work that requires …
News Release
The Telomere-to-Telomere (T2T) Consortium has generated the first truly complete sequence of a human Y chromosome - the final human chromosome to be fully sequenced.
… sequence particularly difficult to complete. Assembling sequencing data is like trying to read a long book cut into … of the human genome, the T2T Consortium applied new DNA sequencing technologies and sequence assembly methods, as well as …
Research Funding
GS-IT provides sequence analysis tools and software to scientists who rely on genomics in their research.
… … Grantees … Program Staff … Related Content … Genome Sequencing Informatics Tools (GS-IT) provides "researcher … biological, biomedical and clinical research. … Genome Sequencing Informatics Tools … Genome Sequencing Informatics Tools … GS-IT provides sequence …
News Release
NHGRI researchers have produced the first end-to-end DNA sequence of a human chromosome. The results show that generating a precise, base-by-base sequence of a human chromosome is now possible, and will enable researchers to produce a complete sequence of the human genome.
… incredibly long, consisting of about 6 billion bases, DNA sequencing machines cannot read all the bases at once. … cell. The authors and their colleagues capitalized on new technologies that can sequence long segments of DNA. Instead … community weigh in and ensure the final product is high-quality,” Miga said. The effort is part of a broader …
The Genomics Landscape
In the July 2020 edition of The Genomics Landscape, NHGRI Director Eric Green recalls the White House event announcing the draft human genome sequence.
… had also accomplished a series of other goals, including sequencing the genomes of a set of model organisms. In fact, … antibody tests in COVID-19 response Swimming with the high-tech sharks to improve COVID-19 testing In a Q&A with … (R21) Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01) …
News Release
Scientists have published the first complete, gapless sequence of a human genome, two decades after the Human Genome Project produced the first draft human genome sequence.
… will empower genetic studies of human disease. The full sequencing builds upon the work of the Human Genome Project , … genomic variation, disease and evolution.” The cost of sequencing a human genome using “short-read” technologies, which provide several hundred bases of DNA …