Search Results
The Genomics Landscape
In the July 2019 edition of The Genomics Landscape, NHGRI Director Eric Green reflects on the milestones of the Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT) Program as it reaches completion.
… of Child Health and Human Development (NICHD), the Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT) … for this screening. The recent advances in DNA sequencing technologies have triggered a growing interest in the use of … conditions. Since these conditions have disproportionately high morbidity and mortality in non-European populations, …
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… your health. We do this by getting a DNA sample from you, sequencing most or all of your genes, and comparing that to … tests that look for health problems such as diabetes and high cholesterol, as well as for genetic testing. … JL, Iben J, Sanchez-Pulido L, Cougnoux A, Platt FM, et al. High incidence of unrecognized visceral/neurological …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… translational genomics. Developing applications of genome technologies for the oncology clinic is an important priority … … Paul Meltzer, functional genomics, molecular profiling technologies, osteosarcoma profiling, melanoma profiling, … … Paul Meltzer, functional genomics, molecular profiling technologies, osteosarcoma profiling, melanoma profiling, …
News Release
Funding to advance understanding of RNA biology and development of RNA-based technologies
… understanding of RNA biology and development of RNA-based technologies. … The National Institutes of Health (NIH) has … acid (RNA) , as well as the creation of RNA-based technologies. "These awards represent an exciting … Molecular Foundations for Biotechnology program . RNA sequencing and the mapping of RNA modifications have gained …
Educational Resources
A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes.
Educational Resources
Northern blot is a laboratory technique used to detect a specific RNA sequence in a blood or tissue sample.
Educational Resources
Population genomics is the application of genomic technologies to understand populations of organisms.
… … Population genomics is the application of genomic technologies to understand populations of organisms. … Gene, … genomics is the large-scale application of genomic technologies to study populations of individuals. For … … Population genomics is the application of genomic technologies to understand populations of organisms. … …
The Genomics Landscape
In the October 2019 edition of The Genomics Landscape, NHGRI Director Eric Green focuses on recent efforts to make the human genome reference sequence useful to basic and clinical researchers and how increasing the representation of human genomic variation will remain key components of NHGRI’s Human Genome Reference Program.
… and expand their expertise, infrastructure, systems, and technologies in genetics and genomics. The summit, which aims … were difficult to “read out” completely using the DNA-sequencing methods available at that time. In addition, the … to be aligned and organized. Such a reference must be high quality and, preferably, enhanced over time as new …
Profile
Reflecting on his NIH career, Dr. Smith recounts his journey from researcher to program director in a conversation with NHGRI science writer Sonja Soo, Ph.D. He looks ahead to a retirement filled with traveling, spending time with friends and family, playing pickleball and brewing ale.
… my first paper on population genetics of feral pigs as a high school student. I was super fortunate that one of my … I chose to focus on the controversy around recombinant DNA technologies. I remember flipping through the pages of the … Project for three years. My focus was on developing DNA sequencing capabilities, which were applied to generate …
Outreach
The Genome: Unlocking Life's Code exhibition celebrates the 10th anniversary of the initial sequencing of the human genome.
… the Smithsonian Institution in Washington, D.C. opened the high-tech, high-intensity exhibition Genome: Unlocking Life's … for the National Institutes of Health. Already, Life Technologies Foundation, the philanthropic arm of Life … exhibition celebrates the 10th anniversary of the initial sequencing of the human genome. … Human Genome Sequencing, …