Search Results
The Genomics Landscape
In the March 2019 edition of The Genomics Landscape, NHGRI Director Eric Green details ClinGen, the first FDA-recognized Public Human Genetic Variant Database.
… of the National Advisory Council for Human Genome Research Model Organisms in the 20th Century: Historical, Philosophic …
ISCC-PEG
A list of organizations and federal agency partners that have members in the Inter-Society Coordinating Committee for Practitioner Education in Genomics (ISCC-PEG).
The Genomics Landscape
In the February 2024 issue of The Genomics Landscape, NHGRI Director Eric Green spotlights the Genome Statute and Legislation Database, which recently received a major revamp to help researchers, policy analysts, and the public more easily find state-level legislation related to genomics.
… states. Additionally, most state-level legislative databases have limited information available or have barriers …
News Release
UDN expands the footprint of the network with a new metabolomics core and increased model organism capabilities.
… "The UDN is pioneering a new personalized medicine model for helping those patients who have historically been … sequencing, metabolomics and assessing patient variants in model organisms to give clinicians new, powerful information … core at Baylor College of Medicine and the model organism screening center at Baylor College of Medicine and …
Educational Resources
In biology, an organ (from the Latin "organum" meaning an instrument or tool) is a collection of tissues that structurally form a functional unit specialized to perform a particular function.
News Release
NIH awards more than $64 million to for a database of human cellular responses called the Library of Integrated Network-based Cellular Signatures or LINCS.
… than 11,000 perturbational conditions in several cellular model systems. Cellular phosphor-signaling and epigenetic …
About NHGRI
Established in 1989, NHGRI collaborates with the scientific and medical communities to catalyze genomic breakthroughs.
News Release
Researchers build a statistical model using family health history to improve disease risk assessment
Researchers at the National Human Genome Research Institute (NHGRI) have developed a new statistical model that can predict the risk for developing diseases by combining information about family member health and lifestyle factors from family members.
… Institute (NHGRI) have developed a new statistical model that can predict the risk for developing diseases by … used type 2 diabetes mellitus (T2D) as the disease model for their study. An estimated 30 million people in the … Marcum and his colleagues aimed to create a statistical model that could be used as a general tool for assessing …
News Release
NHGRI researchers are studying the link between Parkinson's disease, and a rare disorder, Gaucher disease, by cross-breeding mice with the disease mutations.
… controlling movement. Midbrain neurons from the new mouse model. The green shows the clumped alpha-synuclein. Image … In the study, the authors used a Parkinson's disease mouse model that carried extra copies of a mutated form of … about the cross-bred mice. Ultimately, this mouse model can be used to develop and evaluate new treatments for …
Research Funding
The primary mission of the Alliance of Genome Resources (the Alliance) is to develop and maintain sustainable genome information resources that facilitate the use of diverse model organisms in understanding the genetic and genomic basis of human biology, health and disease. This understanding is fundamental for advancing genome biology research and for translating human genome data into clinical utility.
… mission of the Alliance of Genome Resources (Alliance), Model Organism Databases (MODs), and the Gene Ontology (GO) Consortium is to …