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Policy Issues
Federally-funded research with human participants must comply with regulations that protect the rights and welfare of the participants.
… and discoveries that could not be otherwise obtained using model organisms or other methods. All federally-funded … of genetic markers for human diseases. While model organisms remain powerful research tools, working with … future research purposes and to be shared broadly through databases. NIH has the same expectations for informed consent …
About NHGRI
NHGRI is advancing human health and spurring innovation by building bridges between our research laboratories and the academic, non-profit and private sectors.
… to proceed pending final negotiation and review. A model agreement developed by the NCI is provided. … of intellectual property rights to the collaborator. A model agreement developed by the NCI is provided. Materials … of confidential research information. Several different model versions of CDA's developed by the NCI are provided. … …
News Release
NIH released a Request for Information seeking comments on the data submission and access process for dbGaP.
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… Jeannine Mjoseth … Databases such as the 1000 Genomes Project and the Exome …
The Genomics Landscape
In the January 13, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., announces the appointment of Valentina Di Francesco as founding director of the NHGRI Office of Genomic Data Science.
… such as the database of Genotypes and Phenotypes (dbGaP), model organism databases (e.g., Mouse Genome Informatics and Xenbase ), and …
The Genomics Landscape
In the August 4, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about the establishment of the Global Biodata Coalition (GBC), which aims to move towards more internationally coordinated, sustainable, and streamlined mechanisms that support the biodata ecosystem.
… develop robust and readily available data resources (e.g., databases and knowledgebases). A number of these resources) … For example, as the genomes of the selected set of classic model organisms (e.g., yeast, fruit fly, nematode, and mouse) … resources emerged. This gave rise to the well-known “model organism databases,” such as the Saccharomyces Genome …
Partner with NHGRI
NHGRI's technologies, inventions and discoveries are available for licensing.
… of Technology Transfer Abstract … Mouse Models Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular … (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI) Murine Model of Niemann-Pick Disease Type C DHHS Reference No.: … Lead Inventor: William J. Pavan, Ph.D., (NHGRI) Mouse Model of Diamond-Blackfan Anemia DHHS Reference No.: …
Jobs at NHGRI
A postdoctoral training position is currently available in the Computational and Statistical Genomics Branch (CSGB) of the National Human Genome Research Institute (NHGRI).
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… between humans and domestic dogs provides an emerging model of aging. … One of the most common misconceptions is … the results obtained with humans. Dogs are a useful model for such comparisons because much of their environment, … translate the age-related physiology experienced by one organism (e.g., humans) to the age at which physiology in a …
Educational Resources
Bioinformatics is a subdiscipline of biology and computer science concerned with the acquisition, storage, analysis, and dissemination of biological data.
… about those sequences. Scientists and clinicians use databases that organize and index such biological information …