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News Release
Using a recently developed DNA base-editing technique, researchers correct accelerating aging disorder.
… Reading … DNA-editing method shows promise to treat mouse model of progeria … Using a recently developed DNA …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… or a genome that shows the physical locations of genes and other DNA sequences of interest. … Chromosome, … of physical locations of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a … type of physical map. Physical maps are used to identify genes or other sequences believed to play a role in health …
Educational Resources
A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
Educational Resources
Mapping is the process of making a representative diagram cataloging the genes and other features of a chromosome and showing their relative locations.
… process of making a representative diagram cataloging the genes and other features of a chromosome and showing their … relative locations. … Genetic Mapping, Recombinant DNA, Genes, Chromosome … Mapping refers to the process of … the relative locations of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a …
Educational Resources
A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next.
Genetic Disorders
Duchenne muscular dystrophy is a rapidly progressive form of muscular dystrophy caused by a mutation in the DMD gene.
Research at NHGRI
NHGRI researchers work with patients and families to understand of how genes influence disease and develop more effective diagnostics and treatments.
… gene discoveries, including the identification of genes responsible for holoprosencephaly, for a variety of … research endeavors extend far beyond searches for disease genes. researchers are studying knock-in mouse with hereditary inclusion body myopathy, developing …
Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
… BRCA1/BRCA2 … BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast … … Breast Cancer, Prostate Cancer, Genetic Mutation, Genes, DNA Repair, Family Health History … BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast …
Educational Resources
A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes.
… can help link an inherited disease with the responsible genes. … Marker, DNA Sequence, Gene, Inheritance … A marker … Markers can reflect random sequences, genomic variants or genes. Markers are used as signposts (or landmarks) in the … can help link an inherited disease with the responsible genes. … Educational Resources …
For Teachers
Tools and resources for teaching the concepts of transcription and translation, two key steps in gene expression
… This anime shows how molecular machines transcribe the genes in the DNA of every cell into portable RNA messages, …