Search Results
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… between genomes.  Uses family-based studies and animal models to identify susceptibility loci, particularly for … organisms and the use of mouse and other small animal models for cancer-related genetic and functional studies.  …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… have not been confirmed by knocking them out in animal models and seeing what happens. "This is a way to do that on …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… personalized medicine and aggressively humanized mouse models. Specifically, we will (i) enhance our Design – Build … in the production of extensively humanized animal models called Genomically Rewritten and Tailored Genetically Engineered Mouse Models (GREAT-GEMMs), an element of our program worthy of …
News Release
The newly launched Impact of Genomic Variation on Function (IGVF) consortium to include 30 U.S. sites.
… By integrating experimental methods with advanced computer models, the IGVF consortium will identify which variants in …
Research at NHGRI
The Translational and Functional Genomics Branch explores the genetic, epigenetic and metagenomic basis of human disorders.
… of humans, microorganisms that live on humans and animal models of genetic disease. TFGB investigators catalyze … approaches and technologies in cell lines and animal models, TFGB investigators are making fundamental discoveries …
Staff
Dr. Ellen Sidransky is a pediatrician and clinical geneticist in the Medical Genetics Branch at the National Human Genome Research Institute.
… analyses, as well as studies utilizing cells, animal models and human brain samples. With funding from the NIH … dopaminergic neurons, astrocytes and macrophages. Mouse models of Gaucher disease have been crossed with Parkinson disease models, demonstrating that deficient glucocerebrosidase …
Health
Knowledge of your family health history can help you and your healthcare providers identify patterns of inheritance and risk factors.
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
Research at NHGRI
The Medical Genetics Branch studies inherited disorders of metabolism and of human development.
News Release
NHGRI researchers will present four platform talks and 55 posters to highlight the institute's diverse portfolio at the 65th annual meeting of ASHG.
… Session #72: Inborn Errors of Metabolism: Novel Disorders, Models, and Observations; Hilton Baltimore Hotel, Holiday … variable selection method for identifying complex genetic models associated with human traits. (Statistical Genetics … GBA1 mutations and synucleinopathies with in vivo mouse models. (Psychiatric Genetics, Neurogenetics and …