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Staff
Dr. Mullikin was the former director of the NIH Intramural Sequencing Center (NISC).
… to analyze large data sets generated by systematic DNA sequencing projects. A highly skilled computational … analysis package called "Image", custom-modified 60 ABI377 sequencing machines to scan 96 lanes, developed a blazingly … changes resulting in synonymous or non-sysnonymous amino-acid changes, splice-site, etc); and has predicted effects of …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… of interest. … Chromosome, Gene, Deoxyribonucleic Acid (DNA), Positional Cloning … A physical map, as related …
Educational Resources
Polymerase chain reaction (PCR) is a laboratory technique used to amplify DNA sequences.
… used to amplify DNA sequences. … Deoxyribonucleic Acid (DNA), DNA Replication, Enzyme, Genome, Primer … …
Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… of DNA needed to turn a gene on or off. … Deoxyribonucleic Acid (DNA), Enzyme, Gene, Gene Expression, Gene Regulation, …
Media Advisory
The National Institutes of Health (NIH) will host researchers from the Telomere-to-Telomere (T2T) consortium, who have now sequenced the remaining 8% of DNA that was unable to be sequenced by the Human Genome Project and has eluded researchers for nearly two decades.
… What: Virtual press conference to announce T2T consortium sequencing a complete human genome Moderator: Eric Green, …
The Genomics Landscape
In the May 2020 edition of The Genomics Landscape, NHGRI Director Eric Green details how NIH is ramping up research on COVID-19; NHGRI's expansion of its Genome Technology Program; and the the DiY Genome: Unlocking Life's Code exhibition toolkit.
… Some research groups are deploying their available DNA-sequencing and genotyping capabilities to perform COVID-19 … that will support investigators developing novel synthetic nucleic acid technologies and a coordinating center, respectively. …
Educational Resources
A restriction enzyme is an enzyme isolated from bacteria that cuts DNA molecules at specific sequences.
… at specific sequences. … Bacteria, Deoxyribonucleic Acid (DNA), Enzyme, Genetic Engineering, Recombinant DNA …
Educational Resources
Transcription is the process of making an RNA copy of a gene sequence.
… of a gene sequence. … Cell, Cytoplasm, Deoxyribonucleic Acid (DNA), Gene, Gene Expression, Messenger RNA (mRNA), …
Educational Resources
Cloning is the process of making identical copies of an organism, cell, or DNA sequence.
Staff
Dr. Randy Chandler is an associate investigator in the Organic Acid Research Section of the Metabolic Medicine Branch in NHGRI.
… Randy Chandler is an associate investigator in the Organic Acid Research (OAR) Section of the Metabolic Medicine Branch … Randy Chandler is an Associate Investigator in the Organic Acid Research Section of the Metabolic Medicine Branch in … Randy Chandler is an associate investigator in the Organic Acid Research Section of the Metabolic Medicine Branch in …