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Educational Resources
A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases.
… Genome-Wide Association Studies (GWAS) … A genome-wide association study (GWAS) is an … with particular diseases. … Genome-Wide Association Studies, GWAS, DNA, Genome, Gene Expression, Gene Variation, …
News Release
NIH-backed African scientists are engaged in a global research endeavor to understand the genetic basis of disease in all populations.
… the most genetically diverse. … A Global Research Endeavor Studies have shown that African populations contain the … oldest and most diverse set of human genes. However, most studies of the human genome have focused on European ancestry … is no lack of enthusiasm for the research. "Many genomics studies have implications for both individuals and …
The Genomics Landscape
In May 4, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., details a report released by the National Academies of Science, Engineering, and Medicine, that provided a series of recommendations for using population descriptors in future genetics and genomics studies.
… methodologies, benefits, and challenges in the use of population descriptors such as race, ethnicity, and ancestry … of recommendations that provide a framework for using such population descriptors in future genetics and genomics studies. While the fields of genetics and genomics have …
Event
On September 16, 2015, the National Human Genome Research Institute (NHGRI) convened a roundtable to discuss the current status of the engagement and inclusion of underrepresented populations in genomics research.
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… Genome-wide association studies involve scanning markers across the genomes of many … strategies to detect, treat and prevent the disease. Such studies are particularly useful in finding genetic variations … … The impact on medical care from genome-wide association studies could potentially be substantial. Such research is …
Research Funding
The PAGE Consortium investigates ancestrally diverse populations to gain a better understanding of how genetic factors influence susceptibility to disease.
… Genome-wide association studies have identified many genetic variants related to … explore initial findings in non-European populations. The Population Architecture using Genomics and Epidemiology … PAGE is defining the epidemiological architecture of cross-population allele frequencies, relative risks, and …
Event
On November 8-9, 2023, NHGRI sponsored its 15th Genomic Medicine meeting, Genomic Medicine XV: Genomics and Population Screening, in Bethesda MD.
… Medicine meeting, Genomic Medicine XV: Genomics and Population Screening, in Bethesda MD. This meeting discussed the current state of population genomic screening in the U.S., as well as barriers and opportunities for expanded population screening, impact on clinical practice and …
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… newsletters, and we may also invite you to join spinoff studies that relate to CLINSEQ®.  Return of Genetic Results: …
News Release
Researchers identified regions of the genome associated with skin color variation in some African populations, furthering skin disease and cancer research.
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… variant, according to the study. Most of the genomic studies conducted on obesity to date have been in people of … variants associated with the condition. Most previous studies on obesity using a GWAS have been conducted with populations of European ancestry; these studies wouldn't have found the SEMA4D genomic variant, which …