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Genetic Disorders
Sickle cell disease is a group of inherited red blood cells disorders.
sickle cell disease is a group of inherited red blood cell disorders. … sickle cell disease is the most common inherited blood …
Educational Resources
Sickle cell disease is a hereditary disease seen most often among people of African ancestry.
sickle cell diseasesickle cell disease is a hereditary disease seen most often …
News Release
Researchers used whole genome sequence data to investigate the origin of the mutation that causes "sickling" of red blood cells.
… debate about the multi-centric or unicentric origin of the sickle allele in favor of the latter, with an estimate that … inherited with the sickle allele that may influence disease severity. 4. we raised the possibility that the … of the sickle allele will help clinicians redefine sickle cell subgroups and treat patients more effectively. this …
News Releases
Researchers explored patients', parents' and physicians' perspectives on the use of CRISPR-Cas9 gene-editing to reverse sickle cell disease.
… on the use of crispr-cas9 gene-editing to reverse sickle cell disease (scd).  … crispr-cas9 is a gene editing technology …
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… jeannine mjoseth … people with sickle cell disease (scd) can experience excruciating pain all over their …
News Release
Researchers have now identified three health conditions for which people with SCT are at increased risk.
… 2.5 to 3 million people have a gene variant associated sickle cell trait (sct) and most never have related health … pulmonary embolism , proteinuria and chronic kidney disease . findings from this first comprehensive review of …
Clinical Research
The INSIGHTS study is exploring sickle cell disease in adults.
… into microbiome and environmental contributions to sickle cell disease and leg ulcers study (insights) study is exploring …
Staff
Vence Bonham is an associate investigator in NHGRI's Social and Behavioral Research Branch and senior advisor to the NHGRI Director on genomics and health disparities. ​
… health inequities. the bonham group also studies sickle cell disease , a condition that will be impacted by emerging …
News Release
NHGRI researchers asked patients, parents and physicians in the sickle cell disease community (SCD) what they wanted and needed to know about genome editing to make informed decisions about participating in genome-editing clinical trials.
… of health, asked patients, parents and physicians in the sickle cell disease community what they wanted and needed to know about …
News Release
NHGRI has appointed Neil Hanchard, M.D., Ph.D., as a clinical investigator within the Medical Genomics and Metabolic Genetics Branch (MGMGB) in the Division of Intramural Research. Dr. Hanchard will head the Childhood Complex Disease Genomics Section within the MGMGB.
… ph.d. … dr. hanchard will lead the new childhood complex disease genomics section. … the national human genome … methods to study several pediatric diseases , including sickle cell disease , severe childhood malnutrition, pediatric hiv …