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Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
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… ZFN must be engineered for each new target DNA sequence. Transcription activator-like effector nucleases (TALENs) In 2009, a new class of proteins called Transcription Activator-Like Effector Nucleases (TALENs) …  arrived to the genome editing scene. Similar to ZFNs, transcription activator-like effector nucleases (TALENs) are …
Event
The Advances in Genomic Technology Development (AGTD) 2022 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) from July 12-14, 2022 at The Jackson Laboratory (Farmington, CT).
… Technology for Highly Parallel Analysis of Variation in Transcription Factors and their DNA Binding Sites Shubham … Break 11:05 a.m. Keynote Single-cell Epigenomics: Gene Regulation at Unprecedented Resolution Panel Discussion with …
Research at NHGRI
The Genetic Disease Research Branch studies how genetic changes affect the structure and function of gene products leading to human disease.
… in understanding how disruptions in signaling pathways and transcription factors contribute to disease. Our …
Educational Resources
Messenger RNA (abbreviated mRNA) is a type of single-stranded RNA involved in protein synthesis.
… mRNA is made from a DNA template during the process of transcription. The role of mRNA is to carry protein …
Research at NHGRI
The Metabolic Medicine Branch houses clinical and laboratory research programs that focus on the development of new therapies for patients with genetic disorders.
The Genomics Landscape
In the February 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the new director of NHGRI's Division of Genome Sciences.
… the Genome Technology Program; the Genomics of Gene Regulation (GGR); and several NIH Common Fund Programs - the …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Office of Scientific Core Facilities.
For Teachers
Lesson plan based on an award-winning DNA from the Beginning website, an animated primer on the basics of DNA, genes and heredity.
… is the "Central Dogma?" What is the difference between transcription and translation of the DNA message? From the … of infection? What type of enzyme is necessary for reverse transcription to take place? From the PROBLEM section: How …