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The Genomics Landscape
In the February 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the new director of NHGRI's Division of Genome Sciences.
… Goes Viral NIH Scientists Find Microbes on the Skin of Mice Promote Tissue Healing, Immunity Researchers Study …
File
… to inactivate or Òknock-outÓ any partic- ular gene in mice bred for this purpose, and this is proving an extremely … For example, vectors have been designed to deliver transgenic DNA into the 66 Genomics and World Health plant … is the production of hepati- tis B surface antigen in transgenic plants for oral immunization. Similarly, a trial …
News Release
NIH is launching a program, Molecular Phenotypes of Null Alleles in Cells (MorPhiC), to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.
… investigating the consequences of knocking out genes in mice at the level of tissues and organs as part of the …
The Genomics Landscape
In the April 2020 edition of The Genomics Landscape, NHGRI Director Eric Green provides an update on the final stage of the Genomics2020 strategic planning process; the NIH website for COVID-19 information, the Gene documentary debut on PBS and more.
… COVID-19 Gene mutation enhances cognitive flexibility in mice, NIH study suggests NIH researchers discover gene for …
Staff
Dr. Ferreira is a staff clinician in the Medical Genomics and Metabolic Genetics Branch and the head of the Skeletal Genomics Unit.
… saturation mutagenesis induces new skeletal phenotypes in mice. Journal of Bone and Mineral Research . 2021 April 27 … replacement therapy; comparative studies in humans and mice . Journal of Bone and Mineral Research . …
News Release
Over the last 20 years, three families have been unknowingly linked to one another by an unknown illness. Researchers at the National Human Genome Research Institute (NHGRI) and other organizations have now identified the cause of the illness, a new disease called CRIA syndrome. The results of their work were published on Dec. 11 in the journal Nature.
… RIPK1 to limit its function in normal cells. However, mice bearing one mutant copy of RIPK1 and one normal copy, as …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… used to control gene activity have many similarities in mice and humans. … What are the benefits of comparative …
Archive
… 1981-82: First Transgenic Mice and Fruit Flies … Archive …
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… They do not seem to be valid across species, such as in mice, dogs, and wolves. To see why the epigenetic clocks in …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… studies of cultured cells, bacteria, fruit flies, mice and other organisms. Many of the pathways identified in …