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Educational Resources
A lymphocyte is a type of white blood cell that is part of the immune system.
… lymphocyte … a lymphocyte is a type of white blood cell that is part of the immune system. … lymphocytes, … immune system. there are two main types of lymphocytes: b cells and t cells . the b cells produce antibodies that are …
Dr. Pamela Schwartzberg is a senior investigator in NHGRI's Genetic Disease Research Branch.
… antigen receptors: surface immunoglobulins (ig) on b cells, and t cell receptors (tcr) on t cells. together with … … pamela schwartzberg, m.d., ph.d. … pamela schwartzberg, white blood cells , immune system, infection, immunization … pamela …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… but its presence is necessary for the generation of white blood cells called t follicular helper (tfh) cells in response to a …
News Release
A team from the NIH has surmounted a major obstacle to testing potential drug therapies for a rare, genetic condition called Gaucher disease.
… medicine that they have succeeded in coaxing cultured cells to exhibit the signature traits of the disease. using … enlargement of the liver and spleen, a low number of red blood cells , easy bruising caused by a decreased blood … accumulated glucocerebroside is the macrophage, a type of white blood cell . macrophages are cellular housekeepers that …
News Release
NIH researchers identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring strokes, beginning early in childhood.
… of the same gene in patients with a similar type of blood vessel inflammation. … the nih group first encountered … ada2 deficiency causes a faulty function in a subset of white blood cells called monocytes/macrophages. the faulty …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… over 2 times more likely to die from prostate cancer than white men. hispanic/latino and asian-american men are less … or a burning feeling. erection may hurt and there can be blood in the urine or semen. pain may also occur in the back, … and tissue around the prostate to check if the cancer cells have spread (called metastasis). sometimes the surgery …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… structures located inside the nucleus of animal and plant cells . … chromosomes are thread-like structures located … telomere dna is gone, the cell cannot replicate and dies. white blood cells and other cell types with the capacity to divide …
Genetic Disorders
Klinefelter syndrome is a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility.
… being the xy/xxy mosaic. in this variation, some of the cells in the male's body have an additional x chromosome, and … used to confirm the diagnosis. in this procedure, a small blood sample is drawn. white blood cells are then separated from the sample, mixed …
The Genomics Landscape
In the June 2020 edition of The Genomics Landscape, NHGRI Director Eric Green details NHGRI's new Diversity in Genomics Workforce Initiative.
… this ceremonial event took place in the east room of the white house, where politicians, ambassadors, scientists, … that affects hemoglobin. the condition distorts red blood cells into a sickle (or crescent) shape that then clog blood
News Release
NHGRI researchers have identified new genes associated with the Erdheim-Chester disease (ECD) and some possible new therapies.
… approximately 600 people in the world, were published in blood advances . … "the discovery of new genes associated … ecd is caused by the accumulation of specialized white blood cells called histiocytes in different organs. the resulting …