Search Results
Educational Resources
A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome.
… used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome. … DNA … of cloned segments of DNA across a genomic region, while a sequence contig provides the actual DNA sequence of a genomic region. … A contig is a series of …
Profile
Jim Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics.
… pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics. … Anna … Human Genome Project in 1997, and the draft human genome sequence was finished just before I moved to NHGRI in 2003. Seeing the whole progress, from the very early days of Sanger sequencing …
Research Funding
A collaborative large-scale genome sequencing effort to identify rare risk and protective variants contributing to multiple common disease phenotypes.
… Disease Genomics (CCDG) are a collaborative large-scale genome sequencing effort to comprehensively identify rare … NHLBI. We currently estimate that the CCDG program will sequence approximately 100K whole genomes and 125K whole exomes during the life of the …
Staff
Jennifer Strasburger was the lead Genomic Program Administrator (GPA) for NHGRI as well as the co-chair for the NHGRI Data Access Committee (DAC).
… M.S. … Ms. Jennifer Strasburger joined the National Human Genome Research Institute's (NHGRI) Extramural Research … and intramural investigators in depositing genomic data into public repositories such as dbGaP and AnVIL . Ms. … (GPA) for NHGRI as well as the co-chair for the NHGRI Data Access Committee (DAC). … Jennifer Strasburger, Data …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… researchers use a variety of tools to compare the complete genome sequences of different species. By carefully comparing … protein is produced by any given gene is determined by the sequence in which four building blocks - adenine (A), thymine … NHGRI has sequenced many varieties, providing critical data for understanding genetic variation. DNA sequencing …
News Release
New grants totaling approximately $29.5 million will enable scientists to generate and maintain the most comprehensive reference sequence of the human genome.
… to generate and maintain the most comprehensive reference sequence of the human genome. The awards, made over five years pending the … research studies that use or analyze human genomic data rely on the established reference sequence of the human …
News Release
NIH leaders are calling for the scientific community to develop a consensus on the appropriate use of race and ethnicity in biomedical research.
… on its appropriate use in research . National Human Genome Research Institute (NHGRI) Director Eric D. Green, … NHGRI and NIMHD to discuss the use of race and ethnicity data in genomics, biomedical, and clinical research , and its … the scientific rigor in collecting racial and ethnic data, especially in clinical settings; standardize …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… The National Human Genome Research Institute (NHGRI) launched a public research … to identify all functional elements in the human genome sequence. … In April 2003, the finished sequence of the human … sequences from other vertebrate genomes, identified from whole genome shotgun assemblies or obtained by direct …
Staff
Dr. Gerard Bouffard directs the Bioinformatics Group at the NIH Intramural Sequencing Center (NISC).
… University, where he combined his interests in early genome sequencing of the Escherichia coli genome with the … restriction endonuclease mapping data with published DNA sequence fragments to target and close gaps in the genomic … NIH Intramural Sequencing Center (NISC), bioinformatics, whole exome sequencing … Gerard Bouffard, NIH Intramural …
News Release
Three practical strategies for reducing the risk of re-identification, the process by which anonymized personal genomic data are matched with the owner.
… Sheena Faherty, Ph.D. … Data sharing is key to the success of medical research, and … & Health (GA4GH) and funded in part by the National Human Genome Research Institute (NHGRI). The Beacon Project tests … in any genome in a given beacon, but keeps all other sequence data concealed. This would allow a clinician to …