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New research reveals unintended consequences of inappropriate medical food use in managing patients with a type of metabolic disorder

Read moreBethesda, Md., Thurs., Aug. 13, 2015 - In two studies appearing online August 13, 2015 and in the August issue of Genetics in Medicine, researchers note that medical foods, including those given to patients with methylmalonic acidemia (MMA), are not subject to the same scrutiny as therapeutic drugs. A medical food, as defined in the Orphan Drug Act of 1983, is regulated as a food by the Food and Drug Administration and intended to be used under medical supervision. Read more


A new role for zebrafish: larger scale gene function studies

Read more Bethesda, Md., Fri., June 5, 2015 - A relatively new method of targeting specific DNA sequences in zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health. Read more


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Highlights
Genome Advance of the Month

Gene-disease association data could improve drug development

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Drug development is a risky business. More than half of candidate drugs that look promising in the research lab will ultimately fail. More than a quarter of drugs that reach the clinical trial stage will be rejected as ineffective. June's Genome Advance of the Month focuses on how drug development success rates could be improved by using known genetic associations to help choose research targets. Read more

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Last Updated: August 13, 2015