Clinical Research

NHGRI Institutional Review Board


The National Human Genome Research Institute (NHGRI) Institutional Review Board (IRB) is responsible for protecting the rights and welfare of the human subjects of research conducted by intramural investigators at NHGRI.

All intramural research protocols involving human subjects must be submitted for review by the NHGRI IRB. These Web pages contain the instructions, forms and relevant links for submitting a research protocol to the IRB.

IRB News and Updates

November 25, 2015

The NHGRI IRB is serving as the central IRB of record for the Undiagnosed Disease Network, with 10 recruiting sites and 16 overall sites involved in human subjects research.  

The NHGRI IRB has developed the following new documents, which can be found in the Forms, Templates and Guides section of this website:

The NHGRI intramural research program is complying with the NIH Genomic Data Sharing Policy.  Please refer to for general information.  Additional implementation documents for NHGRI intramural investigators can be found at



Victoria Willits
IRB Coordinator
10 Center Drive, CRC
Building 10 CRC, Room 6-3330
Bethesda, MD 20892-1611
Phone: (301) 496-1906

Tara L. McDonough, CIP
NHGRI IRB Administrator
10 Center Drive
Building 10 CRC, Room 6-3330
Bethesda, MD 20892-1611
Phone: (301) 827-0026

Sara Chandros Hull, Ph.D.
Director, NHGRI Bioethics Core
Chair, NHGRI Institutional Review Board
Phone: (301) 435-8712

Ben Berkman, J.D., M.P.H.
Deputy Director, NHGRI Bioethics Core
Phone: (301) 496-1531

Grisel Lopez, M.D.
Staff Clinician, NHGRI Medical Genetics Branch
Vice Chair, NHGRI Institutional Review Board

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Last Updated: November 25, 2015