NHGRI plans to continue overseeing and supporting the general genomics activities of the MODs and Alliance and recognizes the value of organism-specific work performed by the individual MODs and their role in understanding the genome.
NHGRI also recognizes the value of coordinated and integrated activities facilitated through the Alliance. In accordance with this vision, since 2016 NHGRI has gradually restructured the funding landscape away from individual MODs and towards a centralized Alliance. Overall funding for combined Alliance and MOD activities have remained mostly stable over this time.
The MODs and Alliance are cooperative agreements that undergo standard NIH scientific review and programmatic management. In addition, NHGRI convened an external scientific panel in April 2018 to review progress made by the Alliance and provide general recommendations.
NHGRI recognizes that biomedical investigations in model organisms have moved beyond genomics to metabolomic and proteomic studies, areas where NHGRI has less expertise to establish priorities. Thus, NHGRI is also looking to work with other NIH Institutes and Centers, along with other International Funding Agencies, to developing sustainable funding models that keep these resources relevant to the cutting edge of biomedical research, both genomics focused and beyond.