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News Release
National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration. The study may inform the development of treatments for hearing loss in humans.
… and zebrafish are visually quite different, but at a genomic level, they share more than 70% of their genes. This genomic similarity offers the potential for researchers to … would like to unravel.” Using a combination of genomic techniques and computational-based machine learning, …
Educational Resources
Teaching tools to present the foundations of genomics to students and help them understand the impact of genomics in their lives.
… Genomics Education, Genomics Literacy, Genomics 101, Genetics 101, Teaching Genetics, …
News Release
A new study by researchers at the National Human Genome Research Institute (NHGRI) is challenging traditional practices for validating DNA sequencing results.
… more accurate than newer methods." In addition, several studies in recent years have suggested that NGS can identify differences in the DNA sequence - called genomic variants - as accurately as Sanger sequencing. To … an NHGRI DNA sequencing project aimed at examining the genomic make-up of 1,500 mostly healthy individuals. Dr. …
News Release
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
… ancestral groups substantially improves identification of genomic variants associated with blood lipid levels. … ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood … the need to include as many diverse groups of people in studies as possible. Credit: Harry Wedel, NHGRI. Lipids are …
15 Ways Genomics Influences Our World
Genomics is advancing the study of individual and communities of microbes.
News Release
Researchers sequence the genomes of healthy participants, then analyze the data to find presumed, mutations that might lead to a genetic condition.
… on its head. Instead of trying to find a mutation in the genomic sequence of a person with a genetic disease, they … volunteers whose genomes were examined, about 100 had genomic variants predicting that they would have a rare … research setting. Once they identified participants with genomic mutations, researchers called them back to the clinic …
News Release
Using a virtual reality buffet, researchers studied the hundreds of small decisions mothers make while selecting food for their children.
… why receiving information about their children's genomic risk of obesity led some mothers to make healthier … who received the strongest messages about their children's genomic risk for obesity were less subject to a type of … approach to assess research participant behavior in future studies using the VR buffet. "We hope that this work will …
News Release
An international team of researchers including NIH has completed the first comprehensive characterization of genomic diversity across sub-Saharan Africa.
… has completed the first comprehensive characterization of genomic diversity across sub-Saharan Africa. The region is the most genetically diverse in the world, yet few studies have looked into genomic risk factors for disease in Africa. … genotyping and whole-genome sequence data to explore the genomic-variation landscape of several African …
Clinical Research
A study where both genotypic (individual genetics) and phenotypic (individual disease characteristics) patient data would be analyzed using advanced data-analytics programs to derive meaningful associations for the development of prevention, management and treatment strategies.
… KM, Chong SN, Chandrasekharappa SC, Mullikin J, Liu PP. Genomic Landscape of Patients with Germline RUNX1 Variants … oncology because of the rare opportunity to monitor the genomic evolution of cancer from a pre-cancer population in … More widespread access to genomic medicine vital for studying a rare, undiagnosed blood …
Genomics and Medicine
The categories for the notable accomplishments of research are defined as research that uses genomics to generate or study.
… to generate or study. Category Information Content Genomic Medicine Resource Genomic medicine educational materials or guidelines. Pilot … a need for broader research for the systematic uptake of genomic research findings and other evidence-based practices … for notable accomplishments : Involve use of patients’ genomic variant information in clinical decision making. …