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Fact Sheets
Epigenomics is a field in which researchers chart the locations and understand the functions of all the chemical tags that mark the genome.
… by changes in DNA sequence, infectious agents such as bacteria and viruses, or environmental agents. Now, however, …
News Release
NIH researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children.
… Inflammation is the body's natural response to invading bacteria or viruses. The body releases chemicals that cause …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… method. Modeled on a defense mechanism evolved by bacteria against viruses, CRISPR/Cas9 activity was first …
15 Ways Genomics Influences Our World
Genomics is altering a genome with unparalleled efficiency and precision.
… that they could borrow tools from the immune system of bacteria  and develop "bacterial scissors" for surgically …
News Release
Principal investigator-mentors guide new scientists to their next chapter.
… housekeepers, are responsible for destroying foreign bacteria inside white blood cells as well as breakdown …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
… genomes are much smaller compared to the genomes of most bacteria and microorganisms. Scientists  showed that it was …
Fact Sheets
La genómica comparada es un campo de la investigación biológica en el que los investigadores usan una variedad de herramientas para comparar las secuencias del genoma completo de distintas especies. ​
… globo, la mosca de la fruta, la ascidia, la ascáride y la bacteria Escherichia coli. En el caso de algunos organismos, …
Educational Resources
A cell is the basic building block of living things.
… of numerous eukaryotic cells, while many microbes, such as bacteria, consist of single cells. An adult human body is …
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… point of view, inflammation helps us survive. From the bacteria's point of view, inflammation is something to be …
Staff
Dr. Heidi Sofia served as a program director in the Division of Genomic Medicine at the National Human Genome Research Institute from 2010-2023.
… transcriptional responses to diverse stress signals in bacteria. Molecular Cell , 27: 793-805. 2007. [ PubMed ] …