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News Release
NHGRI researchers collaborated with physicians and medical geneticists worldwide to create the Atlas of Human Malformation Syndromes in Diverse Populations.
… the Atlas of Human Malformation Syndromes in Diverse Populations. Health care providers can use the new atlas to … the Atlas of Human Malformation Syndromes in Diverse Populations with collaborators around the world. Credit: … in Africa. "We found ourselves struggling to diagnose the African children," Dr. Kruszka said. "We were doing our best …
Leadership Initiatives
NHGRI aims to ensure all populations are knowledgeable about and can participate in genomics research.
… Genome Research Institute (NHGRI) wants to ensure that all populations are knowledgeable about the science underpinning … Cooperative Study of Hereditary Prostate Cancer in African Americans Collaborative study with Howard University … the genes involved in hereditary prostate cancer in African-American men. Attention Deficit Hyperactivity …
About Genomics
Appropriate use of population descriptors in scientific research is critical for the advancement of genomic science and human health for all.Â
News Release
The largest genomic study on type 2 diabetes in Africans to date has recently been published in Nature Communications and reports the most recent findings of the ongoing Africa America Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two decades.
… . The lead variant at this locus is rare in other world populations, highlighting a benefit of studying diverse populations. By conducting functional studies of this locus … of the Genomics of Type 2 Diabetes in Africans Identifies African-specific Risk Locus … The largest genomic study on …
News Release
This publication and the release of the accompanying data address knowledge gaps across genomics and are certain to have a continuing impact in the field.
… in Nature addresses this lack with a study of 426 African individuals, representing 50 ethnolinguistic groups. … a continuing impact in the field. Geographical regions and populations of origin for H3Africa whole genome sequence … with WGS data from the 1000 Genomes Project and the African Genome Variation Project are included for comparison …
Event
On September 16, 2015, the National Human Genome Research Institute (NHGRI) convened a roundtable to discuss the current status of the engagement and inclusion of underrepresented populations in genomics research.
… status of the engagement and inclusion of underrepresented populations in genomics research.  … NIH Intramural … Lane … Inclusion and Engagement of Underrepresented Populations in Genomics … On September 16, 2015, the National … status of the engagement and inclusion of underrepresented populations in genomics research. … On September 16, 2015, …
Research Funding
The PAGE Consortium investigates ancestrally diverse populations to gain a better understanding of how genetic factors influence susceptibility to disease.
… need to further explore initial findings in non-European populations. The Population Architecture using Genomics and … causal genetic variants across approximately 100,000 African Americans, Asian Americans, American Indians, … … The PAGE Consortium investigates ancestrally diverse populations to gain a better understanding of how genetic …
Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… significance of ancestry-related genomic variation in African-Americans. … GENE-FORECAST® will test the working … between the distinct genomic variation characteristic of African-Americans (AA) and the exposome of social … and phenotypes (e.g. coronary artery calcification) in African-Americans (AA). To examine the associations between …
Event
On November 8-9, 2023, NHGRI sponsored its 15th Genomic Medicine meeting, Genomic Medicine XV: Genomics and Population Screening, in Bethesda MD.
… as appropriate Variants and conditions to be screened for Populations to screen, including appropriate ages and other …
News Release
Researchers show critical association between diabetes and previously unlinked ZRANB3 gene.
… may influence susceptibility to the disease in sub-Saharan African populations. The gene could also influence the development of … Although the role of ZRANB3 in T2D was discovered in African populations (which have been vastly underrepresented …