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Educational Resources
Evolution is the process by which organisms change over time.
… … Genetic Mutation, Genetic Variation, Gene Expression, Charles Darwin, The Origin Of Species, Genes … Evolution, as …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… for gene therapy as a treatment for NPC1 disease," said Charles P. Venditti, M.D., Ph.D., senior investigator in the … disease, gene therapy, NPC1 gene, William Pavan, Charles Venditti … NIH researchers demonstrated that gene …
News Release
The Physician-Scientist Development Program helps physicians develop research programs dedicated to the disorders they specialize in.
… "The clinical problems are close enough at hand." Charles Venditti, M.D., Ph.D., himself an alumnus of the … programs, Peter McGuire M.D., Leslie Biesecker M.D., Charles Venditti, M.D. Ph.D. … The Physician-Scientist …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… therapy we have developed so far to treat MMA," said Charles Venditti, M.D., Ph.D., senior author and investigator … adeno-associated virus, AAV, methylmalonic acidemia, MMA, Charles Venditti M.D. Ph.D., AAV and liver cancer … NIH …
News Release
Researchers recommend more rigorous clinical study of dietary management practices for patients with IEMs, which may result in reformulating some medical foods.
… with many succumbing in the first decade of life," said Charles Venditti, M.D., Ph.D., senior investigator and head … errors of metabolism, IEMs, methylmalonic acidemia, MMA, Charles Venditti, cobalamin C, cblC, Kevin Strauss M.D., …
Research at NHGRI
CRGGH develops a comprehensive staff and training program that uses genomic approaches to study human health and to reduce/eliminate health disparities.
… Trainees Over the years, Dr. Rotimi has provided a wonderful environment for the training … of scholars from underrepresented populations. … Dr. Charles N. Rotimi is the Director of the Center for Research on …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… PMCID: PMC1617227. Musani, S. K., Shriner , D ., Liu, N., Feng, R., Coffey, C. S., Yi, N., Tiwari, H. K., and … Doumatey, A., Huang, H., Zhou, J., Christman, M. F., and Rotimi, C. N. 2009. Transferability and fine- mapping of … PMC2996945. Meilleur, K. G., Doumatey, A., Huang, H., Charles, B., Chen, G., Zhou, J., Shriner , D ., Adeyemo, A., …
News Release
More research must be done to understand the interactions of ancient genes with modern environments.
… of ancient genes with modern environments," said Charles N. Rotimi, Ph.D., co-author of an opinion article published …
The Genomics Landscape
In the November 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 25th anniversary of NHGRI's Intramural Research Program.
… two NHGRI Intramural investigators, William Gahl and Charles Rotimi, were elected  into the National Academy of Medicine. … information, see the All of Us  announcement .  …  Dr. Charles Rotimi, Chief of the NHGRI Intramural Metabolic, …
News Release
Researchers identified 13 gene regions that influence cholesterol levels, some of which affected people differently if they are smokers or former smokers.
… on our susceptibility or resistance to diseases," said Charles N. Rotimi, Ph.D., CRGGH director and chief and senior …