Search Results
15 Ways Genomics Influences Our World
Genomics is ending diagnostic odysseys for patients with rare diseases.
… common than we previously thought, and these mutations don't seem to cause disease at the same rate in everyone who has them. In other words, there are still factors we don't understand that determine whether or not a PRNP …
News Release
On its 15th anniversary, National DNA Day and NHGRI shared its genomics expertise to explain the importance of genomics in our everyday lives.
… about ethnicity and family health history, so if you don't know this information or aren't easily "categorized" … relatives or generations of a family, and genetic risks don't always surface in every generation, making them hidden. …
Genetic Disorders
Trimethylaminuria is a metabolic condition in which an individual is not able to convert trimethylamine into a compound called trimethylamine N-oxide.
… seems to be more common in women than men, but scientists don't know why. Scientists suspect that female sex hormones, … the functions of the FMO3 enzyme are known, so physicians don't know what other symptoms besides odor may be associated …
Secondary Genomics Findings Service
Frequently Asked Questions and Resources
… a participant for a sample and returning the results.  I don’t understand the data submission requirements. Who can …
Fact Sheets
Genetic mapping offers evidence that a disease transmitted from parent to child is linked to one or more genes and clues about where a gene lies on a chromosome.
… that make up DNA are referred to as markers. DNA markers don't, by themselves, identify the gene responsible for the …
News Release
Four NHGRI researchers share the steps toward a career in genomics with 60 Brooklyn-area high school students.
… across the United States" Dr. Findley said. "Students don't necessarily have to be experts in genomics, but they …
Policy Issues
Most ethical discussions about genome editing center on human germline editing because changes are passed down to future generations.
… F., Haecker, S. E., Werner, M., & Smolenski, J. (2015). Don't edit the human germ line. Nature News, 519(7544), 410. … F., Haecker, S. E., Werner, M., & Smolenski, J. (2015). Don't edit the human germ line. Nature News, 519(7544), 410. …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… she said. "How have the tumor cells mutated so that they don't get picked up by the normally functioning dog immune …
News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… (phenotypic appearances) and self and group identification don't capture the ancestral backgrounds of individuals that …
News Release
The skin microbiota plays an intricate role in the human immune system, directing many immune functions and defending against bacterial pathogens.
… in the body," Drs. Belkaid and Segre report. Most people don't realize the skin microbiota's contribution to their …