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News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… Mjoseth … Investigators with the National Institutes of Health (NIH) have discovered the genomic switches of a … but most of the alterations are found in regions of the DNA that do not carry genes. Scientists have suspected that the variants are in DNA elements called enhancers, which act like switches to control …
Educational Resources
A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome.
… Contig … A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome. … DNA Sequences, …
Educational Resources
Step-by-step instructions and printable folding paper included in the downloadable document.
… NHGRI's Jenny Montooth provides a walkthrough of the step-by-step instructions. …  NHGRI’s Director Eric … competitor, Cardboard Eric, to see who could fold our DNA origami the fastest. Take a look to see who won!  … You may recognize DNA as one of the most well-known biological structures. But what better …
Media Advisory
On April 25, 2023, NHGRI will host a symposium to commemorate two special milestones: the 20th anniversary of the Human Genome Project’s completion and the 70th anniversary of the discovery of the DNA double helix.
… For Immediate Release … On National DNA Day, the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, will host a symposium to commemorate two special …
15 Ways Genomics Influences Our World
Genomics is establishing more robust methods for DNA-based forensic analyses.
… Genomics is establishing more robust methods for DNA-based forensic analyses. … Did you know that forensic analyses of DNA were being used well before the completion of the …  along with other lines of evidence for deducing some elements of a suspect's physical appearance. … If you are …
Talking Glossary
Un codón de terminación es una secuencia de tres nucleótidos (un trinucleótido) en el DNA o el ARN mensajero (ARNm) que señaliza una parada en la sÃntesis proteica de la célula.
… una secuencia de tres nucleótidos (un trinucleótido) en el DNA o el ARN mensajero (ARNm) que señaliza una parada en la … proteica de la célula. … A stop codon is a sequence of three nucleotides (a trinucleotide) in DNA or messenger RNA (mRNA) that signals a halt to protein …
Fact Sheets
Polymerase chain reaction (PCR) is a technique used to "amplify" small segments of DNA.
… (PCR) is a technique used to "amplify" small segments of DNA. … Sometimes called "molecular photocopying," the … technique used to "amplify" - copy - small segments of DNA. Because significant amounts of a sample of DNA are …
Educational Resources
Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded.
… (RNA) … Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded. … Cell, Genetic … often single-stranded. An RNA molecule has a backbone made of alternating phosphate groups and the sugar ribose, rather … deoxyribose found in DNA. Attached to each sugar is one of four bases: adenine (A), uracil (U), cytosine (C) or …
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … … are often used in connection with DNA sequencing. Segments of an organism's DNA, ranging from 100,000 to about 300,000 …
Educational Resources
Antisense is the non-coding DNA strand of a gene.
… Antisense … Antisense is the non-coding DNA strand of a gene. … Non-coding DNA, Messenger RNA, … Protein Synthesis … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template …