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Educational Resources
In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene.
… Genetic Imprinting … In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene. … Genetic Imprinting, …
Educational Resources
Genomic variation refers to diversity in gene frequencies.
… Variation … Genomic variation refers to diversity in gene frequencies. … Genetic Variation, Genetic Testing, … effects. … Genomic variation refers to diversity in gene frequencies. … Educational Resources …
News Release
NHGRI is awarding Genomic Innovator Awards to nine institutions to support the research of 12 early career scientists in the field of genomics. The awards will total up to $27 million over five years.
… The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, is awarding Genomic … the research of 12 early career scientists in the field of genomics. The awards will total up to $27 million over five … Stanford, California Apply CRISPR tools to understand gene regulation related to common, complex diseases. Audrey …
Policy Issues
NHGRI has created the IDE Greenhouse as an educational resource to help increase understanding of the regulation in the genomics context.
… (FDA) Investigational Device Exemption (IDE) regulation ( 21 CFR Part 812 ) oversees clinical research … tests to be in vitro diagnostic devices (IVDs), a type of medical device. As genomic technologies continue to enter … to help understand the regulation in the context of genomics. Genomic studies that were either successfully …
News Release
NIH researchers have identified a gene that makes yeast resistant to a lethal toxin.
… Newly discovered gene helps some yeast endure toxins and can help scientists … yeast colony on sensitive yeast Pictured is a colony of yeast secreting a toxin that kills neighboring yeast … and how K28 may evolve in response. “The intricacies of genomics that mediate these within-species battles are …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… available to scientists and researchers two years ahead of the original Human Genome Project schedule and at a cost … Project covers about 99 percent of the human genome's gene-containing regions, and it has been sequenced to an … series exploring the project's impact on the field of genomics and the careers of those involved. … Lessons …
News Release
CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and triglycerides.
… a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including high-density lipoprotein …
News Release
CMG investigators have made significant inroads in discovering genes underlying Mendelian conditions and have uncovered 470 new, previously unknown conditions.
… and Blood Institute launched the Centers for Mendelian Genomics (CMGs) program nearly four years ago, it was charged with the ambitious task of identifying the genomic underpinnings of as many Mendelian … inherited, and typically caused by a mutation in a single gene. So far, researchers have identified the genomic causes …
Fact Sheet
Today, gene therapy for sickle cell disease is considered experimental and only available to you if you participate in a clinical trial.
… to a certain trial, you should learn about: Phases of a clinical trial. Study outcome(s). How researchers will … in a trial may be dependent on: Your age. Your diagnosis of sickle cell disease. Your response to other treatments. … Step 4: Preparation for stem cell collection (~90 days) Gene therapy requires stem cells to be collected from your …
The Genomics Landscape
In the September 3, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about the Impact of Genomic Variation on Function (IGVF) Consortium, the 2020 Genomic Innovator Awards and more.
… Green, M.D., Ph.D. … As Summer 2020 comes to an end, many of us continue to spend the bulk of our time working from home. If you are seeking some virtual connections to genomics, I would like to offer some “remote learning” … and assaying for specific phenotypes; measuring changes in gene and regulatory element activity; identifying and testing …