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Fact Sheets
Data used to estimate the cost of sequencing the human genome over time since the Human Genome Project.
… For many years, the National Human Genome Research Institute (NHGRI) has tracked the costs associated with DNA sequencing performed at the sequencing centers funded by the … for establishing the DNA sequencing capacity of the NHGRI Genome Sequencing Program. Here, NHGRI provides an analysis …
Research Funding
Funded in 2016 to harmonize, access, and analyze the data produced by the sequencing centers.
… The Genome Sequencing Program Analysis Centers (GSPACs) were funded in … to harmonize, access, and analyze the data produced by the sequencing centers. The GSPACs undertake novel, … of Pharmacy … Participants … Grantees … Program Staff … Genome Sequencing Program Analysis Centers … Funded in 2016 …
Research Funding
The Genome Sequencing Program uses genome sequencing to identify genes and genomic variants underlying human inherited disease.
… The Genome Sequencing Program is consists of the following centers … multiple funding opportunity announcements. … The NHGRI Genome Sequencing Program (GSP) has evolved from NIH's participation …
News Release
NHGRI-funded CSER investigators and colleagues point to need for greater evidence that DNA sequencing helps patients.
… … In the nearly four years since its launch, the Clinical Sequencing Exploratory Research (CSER) program has made … care. … CSER, which is funded by the National Human Genome Research Institute (NHGRI) and the National Cancer … and entire exomes (the protein-coding portion of the genome), Dr. Rehm suggested that there may be too much recent …
Talking Glossary
The genome reference sequence provides a general framework and is not the DNA sequence of a single person.
… Human Genome Reference Sequence … The genome reference sequence provides a general framework and is not the DNA sequence of a single person. … A human genome reference sequence is an accepted representation of …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… In 2003, an accurate and complete human genome sequence was finished and made available to scientists … and researchers two years ahead of the original Human Genome Project schedule and at a cost less than the original … the project took on a wide range of other goals, from sequencing the genomes of model organisms to developing new …
The Genomics Landscape
In the April 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the Telomere-to-Telomere (T2T) consortium's publishing of a collection of papers that reported the first truly complete sequence of the human genome.
… significance of their results.   …  In 2003, the Human Genome Project ended with the generation of an essentially complete sequence of the human genome. The project took the practical approach of using the best-available technologies for sequencing DNA and pushing them to their absolute limits. In …
Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… DNA Sequencing … DNA sequencing is a laboratory technique used to determine the … understanding the function of genes and other parts of the genome. There are now several different methods available for …
The Genomics Landscape
In the February 12, 2021 edition of The Genomics Landscape, Dr. Eric Green talks about the 20-year anniversary of the publications that reported the draft human genome sequence.
… Vision — Generating and analyzing a complete human genome sequence will be routine for any research laboratory, … the 1980s discussing the desirability and feasibility of sequencing the human genome, to the U.S. Department of … Timeline of Events . …  A new NHGRI resource about pediatric mitochondrial disease and COVID-19 is now available …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… researchers use a variety of tools to compare the complete genome sequences of different species. By carefully comparing … of years - is an important step toward understanding the genome itself. It pinpoints genes that are essential to life … biology of living things have changed over time. As DNA sequencing technology becomes more powerful and less …