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Staff
Dr. Paul Liu is NHGRI's deputy scientific director and a senior investigator in NHGRI's Translational and Functional Genomics Branch. ​
… inversions and deletions. Two genes, CBFB and RUNX1 , which encode proteins (CBFb and RUNX1, respectively) that form a dimer for DNA binding and … at the NIH Clinical Center for patients with inherited RUNX1 mutations. One form of CBF leukemia is associated with …
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… 1 NIH RUNX1 Natural History Study Summer 2020 page 1 Dear RUNX1 Natural History Study Participant, Welcome to the first … Thank you very much for your participation in the NIH RUNX1 Study! Sincerely, Study on the Impact of COVID on …
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… NIH RUNX1 Intake Form …
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… NIH RUNX1 Natural History Study Intake Form …
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… NIH RUNX1 Natural History Study Newsletter - Summer 2021 …
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… NIH RUNX1 Natural History Study Newsletter - Spring 2022 …
Clinical Research
A study where both genotypic (individual genetics) and phenotypic (individual disease characteristics) patient data would be analyzed using advanced data-analytics programs to derive meaningful associations for the development of prevention, management and treatment strategies.
… A RUNX1 Longitudinal Natural History Study was launched by a … and long-term clinical research of patients with germline RUNX1 mutations and their families in order to achieve better … and hopefully develop new therapies. People with germline RUNX1 mutations develop a genetic disease called familial …
Staff
Dr. Raman Sood is an associate investigator in the Translational and Functional Genomics Branch and director of the Zebrafish Core at the National Human Genome Research Institute. ​
… or chromosomal rearrangements of the core binding factors, RUNX1 and CBFB. For studies aimed at understanding the … genes. Through the study of mutations in gata1 and runx1 , two of the major transcriptional regulators of … Liu P. 2021. Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development . Blood …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… AG, Horwitz MS, Cheng L, Liu PP. Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent …