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News Release
Researchers have now identified three health conditions for which people with SCT are at increased risk.
… circumstances," said Gregory Kato, M.D., director of the Adult Sickle Cell Center of Excellence at the University of …
Educational Resources
Mitochondria are membrane-bound cell organelles (mitochondrion, singular) that generate most of the chemical energy needed to power the cell's biochemical reactions.
Educational Resources
A centrosome is a cellular structure involved in the process of cell division.
… help separate the replicated chromosomes into the daughter cells. … A centrosome is a cellular structure involved in the …
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A nuclear membrane is a double membrane that encloses the cell nucleus.
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A nucleus is a membrane-bound organelle that contains the cell's chromosomes.
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch. ​
… during leukemia development by microarray analysis with cells from Cbfb-MYH11 knock-in mice, and identified … made novel findings regarding its role in hematopoietic stem cell production (Bresciani, Blood in press). Overall the … BM, Wen Z, and Liu PP. Development of multi-lineage adult hematopoiesis in the zebrafish with a runx1 truncation …
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A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and lipid molecules, especially proteins destined to be exported from the cell.
Educational Resources
A fibroblast is the most common type of cell found in connective tissue.
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… that the genetically altered embryos cannot grow into adult mice. The lack of adult mice limits studies to … disease.   … Researchers begin by harvesting embryonic stem (ES) cells from early-stage mouse embryos four days after …
Educational Resources
Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of chromosomes (one set from each parent).
… Meiosis … Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of … that reduces the number of chromosomes in gametes (the sex cells, or egg and sperm). In humans, body (or somatic) cells …