Search Results
The Genomics Landscape
In the November 2019 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the International Common Disease Alliance's scientific plenary and launch meeting in September, which included an international panel on opportunities emerging outside the U.S., North America, and Europe; discussions about polygenic risk scores; and an overview about data platforms, data sharing, and ethics.
… to develop a graphical display illustrating the scale of human genome sequence. The wall is now enhanced with a … linked to diabetes through a DNA-regulating gene in animal models One little girl’s story highlights the promise of …
Research Funding
The primary mission of the Alliance of Genome Resources (the Alliance) is to develop and maintain sustainable genome information resources that facilitate the use of diverse model organisms in understanding the genetic and genomic basis of human biology, health and disease. This understanding is fundamental for advancing genome biology research and for translating human genome data into clinical utility.
… The primary mission of the Alliance of Genome Resources (Alliance), Model Organism Databases … the genetic and genomic basis of human biology, health and disease. This understanding is fundamental for advancing …
News Release
In a study published in the journal Science, collaborators at NHGRI, the National University of Ireland, Galway, and the Whitney Laboratory for Marine Bioscience at the University of Florida, Augustine, reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ cells in a cycle that can repeat endlessly.
… Prabarna Ganguly, Ph.D. … NHGRI-supported research of Hydractinia  could provide clues to human reproductive … like an unlikely study subject for researchers, but this animal has a rare ability – it can make eggs and sperm for … a surprisingly large number of genes that are like human disease genes, making it a useful animal model for studying …
Media Advisory
With the publication of 16 high-quality reference genomes from across vertebrates, the Vertebrate Genome Project establishes standards for biodiversity genomics and reports discoveries in comparative biology, conservation, and health research
… learn more about biodiversity, human health and disease. … The Vertebrate Genomes Project , part of the Genome 10K  Community of Scientists, today … … Vertebrate Genomes Project produces first set of 16 animal reference genomes … With the publication of 16 …
Fact Sheet
Today, gene therapy for sickle cell disease is considered experimental and only available to you if you participate in a clinical trial.
… to a certain trial, you should learn about: Phases of a clinical trial. Study outcome(s). How researchers will … in a trial may be dependent on: Your age. Your diagnosis of sickle cell disease. Your response to other treatments. Whether you are …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… data on gene expression, as well as surrogate markers of regulatory elements, in different cell fates or cell … element data to construct gene regulatory network models, taking advantage of the dynamics of the system as the … facilitate interpreting the phenotypic consequences (e.g. disease) of genetic variation, particularly in non-coding …
News Release
NHGRI researchers have successfully used facial recognition software to diagnose a rare, genetic disease in known as DiGeorge syndrome.
… the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, and their collaborators, have successfully used … facial recognition software to diagnose a rare, genetic disease in Africans, Asians and Latin Americans. … The …
The Genomics Landscape
In the July 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 10th anniversary of the Undiagnosed Diseases Program.
… That event was extremely helpful in revealing some of the major issues that are on the minds of genome … to direct the program today. With the goal of improving disease management for individual patients and advancing … Interview with Jean McEwen Funding Opportunities Large Animal Testing Centers for Evaluation of Somatic Cell Genome …
Event
On June 17-18, 2021, NHGRI hosts a workshop, Multi-Omics in Health and Disease: Current Applications, Challenges and Future Directions.
… Howard Chang, Stanford University Judy Cho, Icahn School of Medicine at Mt. Sinai Workshop Rationale Moderator: Howard … Chang (Stanford University) 1:05 - 1:15 p.m. Overview of NHGRI’s Strategic Vision Eric Green, NHGRI 1:15 - 1:25 … the Stage - Application of multi-omics to study health and disease Moderator: Judy Cho, Icahn School of Medicine at Mt. …
Educational Resources
Sickle cell disease is a hereditary disease seen most often among people of African ancestry.
… Sickle Cell Disease … Sickle cell disease is a hereditary disease seen most often among people of African ancestry. … Autosome, Birth Defect, Gene, … is a hereditary disease seen most often among people of African ancestry. Caused by mutations in one of the genes …