Search Results
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… for making dramatic, coordinated changes to extensive gene loci in the form of Big DNAs of 50-1000 kb, which enable … sequences for its effect on protein abundance, stability, interactions, turnover and aggregation. In the third specific … combination with another mutation, or in the presence of a drug. The Center will also train early career …
Diversity Center
The University of Texas Rio Grande Valley (UTRGV) has established a Diversity Center for Genome Research that will build UTRGV’s genomics research capacity by 1) expanding genomic research capabilities and discoveries in two innovative research projects; and 2) enhancing the size and quality of the available genomics workforce.
… To rigorously test for genotype-by-environment interactions in NAFLD, this project will use a novel … factors and to foster the study of genotype-environment interactions.  … Center Goals and Objectives … Center Cores …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… in the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory … in different cell fates or cell states. They use the gene expression and functional element data to construct gene … insights gained during the course of the project. These interactions will be important in learning which features are …
CRGGH is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics Branch.
Staff
Dr. Pamela Schwartzberg is a adjunct investigator in NHGRI's Genetic Disease Research Branch.
… SLAM family members are required for proper T:B cell interactions. Therefore, in the absence of SAP, T cells … by demonstrating that they arise from altered T:B cell interactions in the absence of SAP, suggesting potential … therapeutic intervention via inhibition of SLAM family interactions.  Studies of CD8+ T cell function have now been …
Staff
Dr. William A. Gahl is a senior investigator in the Medical Genetics Branch and the director of the NIH Undiagnosed Diseases Program.
… for nephropathic cystinosis, bringing cysteamine to new drug approval by the Food and Drug Administration. His group … aciduria type III, HPS-2, HPS-3 and HPS-9. The gene responsible for HPS-9, PLDN encodes pallidin, a member … which is one of the proteins responsible for membrane interactions that form new vesicles out of existing membrane …
Staff
Dr. Carsten Bonnemann is an adjunct investigator in the Medical Genetics Branch at the National Human Genome Research Institute.
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… which his research team recently identified the causative gene. In its basic research, Dr. Bönnemann's laboratory team explores the role of interactions between muscle and its extracellular matrix in … identification of the LIM domain protein FHL1 as the gene-product mutated in reducing body myopathy. J Clin Invest …
Research at NHGRI
The Office of the Scientific Director provides leadership and managerial oversight for all research and activities in NHGRI's Division of Intramural Research.
… Finally, OSD promotes activities intended to increase interactions among its scientific staff, through seminar …
The Genomics Landscape
In the August 4, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about the establishment of the Global Biodata Coalition (GBC), which aims to move towards more internationally coordinated, sustainable, and streamlined mechanisms that support the biodata ecosystem.
15 Ways Genomics Influences Our World
Genomics helps us understand evolution and protect our biological ecosystems.
… studies are allowing us to appreciate the complex interactions of our world as never before. … Think you know …