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15 Ways Genomics Influences Our World
​Genomics is helping us understand what makes each of us different and what makes us the same.
… Project, researchers began developing tools to detect genomic differences between people. When scientists agreed to … new types of variants  within human genomes. Human genomic variation is particularly important because a very …
Research Funding
The Genomic Variation Program supports large-scale studies of human genetic variation.
… the sequence of DNA among individuals are called genetic variation. Genomic variation explains some of the differences among … variants to functional variation and phenotype. The Genomic Variation Program supports large-scale studies of …
The Genomics Landscape
In the September 3, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about the Impact of Genomic Variation on Function (IGVF) Consortium, the 2020 Genomic Innovator Awards and more.
… of the central challenges in biology is understanding how genomic variation affects genome function to influence phenotypes. … multiple funding opportunities to establish the Impact of Genomic Variation on Function (IGVF) Consortium , the …
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
… Medical Center Multiscale functional characterization of genomic variation in human developmental disorders HG011996 Michael … Irvine California Institute of Technology Center for Mouse Genomic Variation at Single Cell Resolution HG012077 …
Educational Resources
A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next.
… Copy Number Variation (CNV) … A copy number variation (CNV) is when the number of copies of a particular … individual to the next. … Chromosomes, Disease, DNA, Gene Variation … A copy number variation (CNV) is when the number …
News Release
NHGRI researchers have generated the largest catalog of genetic variants associated with physical traits for domesticated dog breeds.
… toward the major role played by genetics in shaping such variation in dogs. … The Power of Comparison In a new study, … sequencing and genome-wide association studies to identify genomic variants associated with sixteen observable … in an animal model. The researchers propose that specific variation in  LCORL  may account for body size difference in …
News Release
Scientists from the 1000 Genomes Project Consortium has created the world's largest catalog of genomic differences among humans.
… Consortium has created the world's largest catalog of genomic differences among humans, providing researchers with … heart disease and other disorders. Understanding how genomic variants contribute to disease may help clinicians … that has produced a valuable resource about human genomic variation," said Eric Green, M.D., Ph.D., director of NHGRI. …
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… gene activity. … To paint a clearer picture of how such variation affects gene activity, Fernando Pardo Manuel de … provide new insights into the effects and roles of genetic variation and parental influence on gene activity in mice and … Jeffrey Struewing, M.D., program director, Division of Genomic Medicine, NHGRI; Andrea Beckel-Mitchener, Ph.D., …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… and regulated in different tissues, and the role that genomic variation plays in modulating that expression. … An Atlas of … bank that researchers can use to study how inherited genomic variants - inherited spelling changes in the DNA code …
Event
NHGRI workshop seeking scientific perspectives for relating genomic variation to human phenotype.
… 2  ( Madison Room ) How and why to approach structural variation and other "hard to measure" variation? Co-Chairs : … strategy to advance our ability to find and characterize genomic variants, the genomic elements in which they reside or that they affect and …