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News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… of Health (NIH) have discovered the genomic switches of a blood cell are key to regulating the human immune system. The … investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system. ​ … Immune system regulation, genomic switches in blood cells, autoimmune disorders, John O'shea M.D., Golnaz …
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague. The study, carried … prior to effective treatment, those with two copies have high mortality rate by the age of 40, but usually live long … fight back. "Inflammation is a process in which white blood cells protect the body from infection. From the host's …
Genetic Disorders
Phenylketonuria is an inherited disorder of metabolism that causes an increase in the blood of a chemical known as phenylalanine.
… disorder of metabolism that causes an increase in the blood of a chemical known as phenylalanine. … Phenylketonuria … disability and other serious problems. Women who have high levels of phenylalanine during pregnancy are at high risk for having babies born with mental disability, …
Outreach
A list of high quality educational activities to engage students on DNA Day.
… Browse through a list of high-quality educational activities to engage students on DNA … Units will culminate in community-focused projects. High-quality professional learning experiences will also be … Education Project (pgEd) includes interactive lessons for high school and college educators to engage their students in …
Educational Resources
A phenotype is an individual's observable traits, such as height, eye color, and blood type.
… observable traits, such as height, eye color, and blood type. … Gene, Heterozygous, Homozygous, Allele, Trait, … observable traits, such as height, eye color and blood type. A person’s phenotype is determined by both their … observable traits, such as height, eye color, and blood type. … Educational Resources …
News Release
Scientists are exploring the genomic and clinical profiles of people with RUNX1 familial platelet disorder.
… ago, Emily* discovered that she had fewer platelets in her blood than most people. Platelets, sticky disc-shaped pieces … turns genes on and off. It also helps stem cells in the blood, known as hematopoietic stem cells, develop and function. These stem cells generate all types of blood cells, such as red blood cells, white blood cells and …
Educational Resources
A lymphocyte is a type of white blood cell that is part of the immune system.
… Lymphocyte … A lymphocyte is a type of white blood cell that is part of the immune system. … Lymphocytes, White Blood Cell, Immune System … A lymphocyte is a type of white blood cell that is part of the immune system. There are two …
Genetic Disorders
Alpha-1 antitrypsin deficiency is an inherited condition that causes low levels of, or no, alpha-1 antitrypsin in the blood.
… causes low levels of, or no, alpha-1 antitrypsin in the blood. … Alpha-1 antitrypsin deficiency (AATD) is an … low levels of, or no, alpha-1 antitrypsin (AAT) in the blood. AATD occurs in approximately 1 in 2,500 individuals. … liver disease can include a swollen abdomen, coughing up blood, swollen feet or legs, and yellowing of the skin and …
Educational Resources
Hemophilia is an inherited disease, most commonly affecting males, that is characterized by a deficiency in blood clotting.
… affecting males, that is characterized by a deficiency in blood clotting. … Hemophilia, Blood Clotting, X Chromosome, Gene, Mutation … Hemophilia is … affecting males, that is characterized by a deficiency in blood clotting. The responsible gene is located on the X …
Clinical Studies
The IDENTIFY Study is a study exploring how prenatal blood test results for the baby might also detect cancer in the mother.
… ask you to share your medical records and will send you a blood collection kit so that you can mail us some blood samples.   How often will I have to come to the NIH? … repeat your evaluation.  … A study exploring how prenatal blood test results for the baby might also detect cancer in …