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The Genomics Landscape
In the January 2024 issue of The Genomics Landscape, NHGRI Director Eric Green announces the appointment of Dr. Adam Phillippy as the founding director of the Center for Genomics and Data Science Research (CGDSR).
Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
FAQ
Addressing the COVID-19 pandemic and what it means to the pediatric mitochondrial disease community.
… disease are sensitive to the effects of viral infections. As a result, children with this disease may …
For Patients and Families
Neglected diseases are conditions that inflict severe health burdens on the world's poorest people.
… the anti-malarial drugs that many take to ward off malaria infections. Still, even at a cost of less than 50 cents a …
Genetic Disorders
Severe Combined Immunodeficiency is a severe, genetic condition of the immune system.
… those affected highly susceptible to life-threatening infections by viruses, bacteria and fungi. Because David's … him into a plastic isolation unit to protect him from infections. He lived in such isolators for nearly 13 years. … an attempt to provide him with the capacity to fight infections on his own and thus free him from the bubble. …
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… pestis does not reduce inflammation in white blood cells acquired from FMF patients and people with one copy of …
News Release
TCF1 (for T cell factor-1) is essential for the creation and persistence of disease-fighting antibodies in the bloodstream.
… required to get good responses to vaccines against viral infections," Dr. Schwartzberg said. If the presence of TCF1 … of vaccines and immune therapies targeting viral infections." The stakes are high. "Almost all successful …
15 Ways Genomics Influences Our World
Genomics is advancing the study of individual and communities of microbes.
… cells? And, even though some microbes can cause dangerous infections, you can't live without others? Viral and … you might not have good thoughts about them. In 2018, infections from the influenza virus have been particularly … genomics is now used routinely to track influenza virus infections , in real time, as the virus spreads across the …
Fact Sheet
Today, gene therapy for sickle cell disease is considered experimental and only available to you if you participate in a clinical trial.
… To collect your stem cells, you will: Be admitted to the hospital for 1–3 days. Be given a medication that causes your … your modified stem cells, you will: Be admitted to the hospital. Receive a chemotherapy drug through an intravenous … track your progress. Medicines to help prevent and treat infections. Outpatient: 2–3 months Once your clinical trial …
Staff
Dr. Jennifer Troyer is the director of NHGRI's Division of Extramural Operations.