Search Results
Event
A joint NHGRI-NCATS hosted meeting bringing together researchers, clinicians, families and patient advocates from around the world to discuss the natural history, disease pathophysiology, genetics and treatments for rare inborn metabolic errors.
… Ph.D. 2:00 - 2:30 p.m. Treatment of CBS Deficient Mice by AAV-Mediated Gene Therapy Warren Kruger, Ph.D. 2:30 - …
Genetic Disorders
Huntington's disease is an inherited neurological illness causing involuntary movements, severe emotional disturbance and cognitive decline.
… of the disease by breeding laboratory animals, such as mice, and attempting to duplicate the clinical features of …
The Genomics Landscape
In the November 2019 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the International Common Disease Alliance's scientific plenary and launch meeting in September, which included an international panel on opportunities emerging outside the U.S., North America, and Europe; discussions about polygenic risk scores; and an overview about data platforms, data sharing, and ethics.
… Schizophrenia risk gene linked to cognitive deficits in mice Scientists unveil search-and-replace genome editing …
Outreach
A list of high quality educational activities to engage students on DNA Day.
… or explore rapid evolutionary change through "rock pocket mice." Resources also discuss artificial vs. natural … relate to society. These topics include: "Transgenetic Mice", "Genetically Modified Foods", "Pharming for …
The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
… Disease Research (CIDR) and the NIH Common Fund's Knockout Mouse Projects (both KOMP and KOMP2). …  NHGRI …
Staff
Dr. Tyra Wolfsberg is the associate director of the Bioinformatics and Scientific Programming Core at the National Human Genome Research Institute.
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… M, Burgess SM, Lin S. A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Office of Scientific Core Facilities.
… Jiang X, Wei M, Jin J, Liu PP, Chen J. Overexpression and knockout of miR-126 both promote leukemogenesis. Blood, …
Archive
… Researchers to Gain Wider Access to Knockout Mice … Archive …
File
… Mike Pazin, Stefanie Nelson (NCI), Joni Rutter (NIDA) Knockout Mouse Phenotyping Program KOMP2 https://commonfund.ni h.gov/KOMP2/ NIH Common Fund Mice Phenotypic Data collection for standardized phenotyping …
Research Funding
Frequently Asked Questions for IGVF RFAs: RFA-HG-20-043, RFA-HG-20-044, RFA-HG-20-045, RFA-HG-20-046, RFA-HG-20-047
… Although perturbations such as a drug, hormone, or gene knockout may be allowable, these should be used to map …