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News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… in recent research published online in july in the journal leukemia , paul liu, m.d., ph.d., asenior investigator and … with a specific kind of relapse-prone acute myeloid leukemia (aml). though aml is generally thought to be a … american cancer society. "we're trying to understand why leukemia patients relapse, and if there are any dna-level …
Staff
Dr. Paul Liu is NHGRI's deputy scientific director and a senior investigator in NHGRI's Translational and Functional Genomics Branch. ​
… liu's research over the years has been the mechanism of leukemia development at the molecular level, using genetic … a common chromosome abnormality in human acute myeloid leukemia . using animal models, dr. liu has illustrated the importance of cbfb-myh11 for leukemia development, and how this fusion gene works. his …
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… diagnosed with a blood cancer called acute lymphoblastic leukemia (or all) in 2003, when he was in his fourth year of … this led him to specialize in treating patients with leukemia , and studying the disease in the laboratory. while … better results by monday. after a number of weeks, the leukemia cells were no longer detectable in his blood, …
Archive
… researchers discover key mutation in acute myeloid leukemia … archive …
Archive
… researchers identify potential drug targets markers for leukemia risk … archive …
Archive
… 2001: fda approves genetics-based drug to treat leukemia … archive …
File
… blood cancers such as myelodysplastic syndrome or leukemia . Newsletter 2 Genomic research team New additions … with R U N X1 to increase a person’s risk of developing leukemia or make their disease more severe? Are there … mutations in R U N X1 that happened after they developed leukemia – this is a bit different than having germline R U N …
News Release
A new study by scientists at NHGRI, suggests that iPSCs do not develop more mutations than cells that are duplicated by subcloning.
… hope to develop new therapies to treat patients with leukemia using their own ipscs. we encourage other …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… changes that lead to certain blood cancers, such as leukemia . although dr. liu acknowledged that the zebrafish is not a proven model for leukemia , its transparent embryos develop in the water away …
Clinical Research
A study where both genotypic (individual genetics) and phenotypic (individual disease characteristics) patient data would be analyzed using advanced data-analytics programs to derive meaningful associations for the development of prevention, management and treatment strategies.
… only receive deidentified information. if i develop leukemia and require a bone marrow transplant can i have the … understand what changes occur in patients who progress to leukemia as compared to those who don’t, since it is believed that leukemia is developed from the blood precursor cells in the …