Search Results
The Genomics Landscape
In the April 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the Telomere-to-Telomere (T2T) consortium's publishing of a collection of papers that reported the first truly complete sequence of the human genome.
… about how genomic data may later be shared in databases can sometimes be an afterthought, making it … form and training materials, which could be used as a model by others in point-of-care settings when collecting …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… researchers, the reasons for using zebrafish as their model organism of choice are as varied as the diseases they study. … For Dr. Brooks' research program, using the zebrafish as a model is both practical and eye-opening."The zebrafish …
Research at NHGRI
The Technology Transfer Office is responsible for transferring NHGRI technologies to the private sector and exchanging research materials with outside groups.
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… such as the database of Genotypes and Phenotypes (dbGaP), model organism databases (e.g., Mouse Genome Informatics and Xenbase ), and …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… Human Genome Project sequenced the genomes of a number of model organisms that are commonly used as surrogates in … as ENCODE (Encyclopedia of DNA Elements) and modENCODE (model organism Encyclopedia of DNA Elements) have compared and …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… way that canines may come to our aid-as a powerful animal model for research into human cancer. … A genetic mutation … which is not inherited but rather arises during an organism's lifetime, alters the protein and causes cells to … cancers are similar, and dogs already have served as a model in cancer research. They were central to immune system …
News Release
Scientists are using an exciting gene editing tool called CRISPR/Cas9 to protect plants from harmful DNA viruses, strengthening the plant's protections.
… called Cas9) allows scientists to snip out segments of an organism's DNA and insert new ones. While using the system to … species was chosen because it is well understood as a model organism, and new findings can be easily applied to other …
Outreach
Frequently asked questions about National DNA Day - a unique day when students, teachers, and the public can learn more about genetics and genomics.
… Society of Genetic Counselors (NSGC), both have online databases available to reach out to genetics professionals …
Fact Sheet
Viruses are bundles of genetic material wrapped in a protein coat that can infect living things.
… ways, including by:    Direct contact with an infected organism, such as being bitten by a mosquito infected with … no symptoms. However, when many viral particles infect an organism's cells at the same time, they may cause anything … acid that make the viruses work differently in the host organism, such as by changing the viral protein coat …
Fact Sheets
Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.
… to DNA found in the cell's nucleus as nuclear DNA. An organism's complete set of nuclear DNA is called its genome. …  … DNA contains the instructions needed for an organism to develop, survive and reproduce. To carry out …