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Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
prostate cancerprostate cancer is a disease characterized by uncontrolled cell growth …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
prostate cancer is the most common cancer in american men aside from skin cancer . one in 6 american men will develop prostate cancer during their lifetime. at this time, more …
News Release
NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… … a key challenge health care providers face in treating prostate cancer is distinguishing the aggressive, potentially … identified a specific genomic signature of some aggressive prostate tumors, which may help health care providers …
Staff
Elaine Ostrander is chief of NHGRI's Cancer Genetics and Comparative Genomics Branch.
… is chief and distinguished senior investigator of the cancer genetics and comparative genomics branch at the … lab uses state-of-the-art genomic approaches to identify prostate cancer susceptibility genes in both high-risk … development and disease, with a specific lab focus on prostate cancer (pc), where they are working both …
Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
… found to be associated with inherited forms of breast cancer . … breast cancer , prostate cancer , genetic mutation, genes, dna …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… the cancer genetics and comparative genomics branch seeks to … the development of various aggressive cancers , including prostate , endometrial, bladder, lung, head and neck, and … of cancer, including (but not limited to) cancers of the prostate, endometrium, lung, bladder, and breast; melanoma, …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… the cancer genome atlas (tcga) was a joint effort of the national cancer institute (nci) and the national human genome research …   tcga study reveals new clues to the genomic diversity of prostate cancers  (2015)   peering at brain and skin cancers …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… kyle davis … receiving a cancer diagnosis can feel like losing control of everything. … its natural defenses, which can then lead to diseases like cancer ," said laura elnitski, ph.d., a senior investigator … a higher chance of survival. but the same isn't true for prostate cancer , where it can indicate more aggressive …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor dna that occurs in five different types of cancer . they also found evidence that this methylation signature may be present in many more types of cancer . the specific signature results from a chemical … from patients with bladder, breast, colon, pancreatic and prostate cancers to determine the accuracy of detection at …
Staff
Abdel Elkahloun is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… to defining exosomes or evs (extra-cellular vesicles) in cancer. in 2014, and in collaboration with dr. roberts at … nci, dr. elkahloun demonstrated that exosomes derived from cancer cells can affect the transcriptomes of surrounding … identifies cxcl14, itgax, and lpcat2 as novel aggressive prostate cancer susceptibility genes. plos genet, 20(11). …