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Educational Resources
Cytogenetics is the branch of genetics that studies the structure of DNA within the cell nucleus.
… of genetics that studies the structure of DNA within the cell nucleus. … DNA, Nucleus, Chromosomes, Fluorescence In … containing DNA that reside within the nucleus of a cell. During cell division, these structures become condensed and are …
Educational Resources
Cloning is the process of making identical copies of an organism, cell, or DNA sequence.
… is the process of making identical copies of an organism, cell, or DNA sequence. … DNA Sequence, Ethics, Cloning … … identical, or virtually identical, copies of an organism, cell or DNA sequence. The phrase “molecular cloning” … is the process of making identical copies of an organism, cell, or DNA sequence. … Educational Resources …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… the blood stem cells to reduce your symptoms of sickle cell disease.  Gene therapies use your own stem cells, while … the complications, treat or prevent symptoms of sickle cell disease. However, this type of gene therapy will neither … In a bone marrow transplant , also called a stem cell transplant, your stem cells are replaced with new stem …
Fact Sheets
Fluorescence in situ hybridization (FISH) provides researchers with a way to visualize and map the genetic material in an individual's cell.
… The first step is to prepare short sequences of single-stranded DNA that match a portion of the gene the … like chemical magnets. Since the researchers' probes are single-stranded, they are able to bind to the complementary … visualize and map the genetic material in an individual's cell. … Fluorescence In Situ Hybridization, FISH, Genetic …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… Experimental Hematology. The American Society of Gene and Cell Therapy has elected Dr. Bodine to serve as President, … into some lineages and eventually become committed to one single type of cell that ultimately enters the blood … (i.e. red cells). Our most recent studies have used single cell approaches to identify the earliest progenitor …
Educational Resources
A vacuole is a membrane-bound cell organelle.
… Vacuole … A vacuole is a membrane-bound cell organelle. … Cell, Organelle … A vacuole is a membrane-bound cell … cells, vacuoles help maintain water balance. Sometimes a single vacuole can take up most of the interior space of the …
Educational Resources
A lysosome is a membrane-bound cell organelle that contains digestive enzymes. Lysosomes are involved with various cell processes.
… Lysosome … A lysosome is a membrane-bound cell organelle that contains digestive enzymes. Lysosomes are involved with various cell processes. … Lysosome, Cell Biology, Virus, Bacteria, Programmed Cell Death, …
Educational Resources
Nucleic acids are large biomolecules that play essential roles in all cells and viruses.
Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
… with antibiotic resistance — and can be passed from one cell to another. Scientists use recombinant DNA methods to …
News Release
Cell Press' "Best of AJHG 2017-2018" includes an article authored by CRGGH researchers Daniel Shriner and Charles Rotimi.
… Amy Bentley … Cell Press has assembled a reprint collection of the "Best of … , entitled "Whole-Genome-Sequence-Based Haplotypes Reveal Single Origin of the Sickle Allele during the Holocene Wet … … Related Content … CRGGH Work Highlighted by AJHG … ​Cell Press' "Best of AJHG 2017-2018" includes an article …