Search Results
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
Genetic Disorders
Klinefelter syndrome is a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility.
Genetic Disorders
Neurofibromatosis is a genetic neurological disorder that can affect the brain, spinal cord, nerves and skin.
… that can affect the brain, spinal cord, nerves and skin. Tumors, or neurofibromas, grow along the body's nerves or on … among all racial groups and affect both sexes equally. The tumors arise from changes in the nerve cells and skin cells. Tumors also may press on the body's vital areas as their size …
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… Jeannine Mjoseth … Cancerous tumors are voracious. Once they have consumed all the oxygen … trials are focused on targeting genetic changes in tumors and helping to boost one's immune system to fight the …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… an aggressive tumor - neither of which are ideal. … How tumors differ from each other - either in different organs or … to the patient's specific tumor. A massive new analysis of tumors, published online April 17 in Epigenetics & Chromatin, … ignored among other issues." Researchers have found that tumors with CIMP are linked to different outcomes for …
Profile
Dr. Joan Bailey-Wilson, who retired in September 2022, looks back on her 42-year career as a scientist and reflects on the rapid growth of the genomics field.
… cancer. We identified the first gene to cause carcinoid tumors in one family we studied. What was truly exciting was … the high-risk genetic variant, diagnose and remove their tumors at a very early stage, and thus save their lives.  It … predict individuals at very high risk of carcinoid tumors. As one of the first in her family to go to college, …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… the inhibitor developed significantly fewer metastatic tumors than control mice that had not been treated. Some …
FAQ
Questions and answers from the September 26, 2022, Multi-Omics for Health and Disease Consortium Pre-Application Webinar.
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… that lead, specifically, to fast-growing and aggressive tumors. Formation or production of tumors-tumorigenesis-can result from genomic alterations that … Identifies somatic genomic alterations that drive sporadic tumors using whole-exome and whole-genome sequencing …
Genetic Disorders
WAGR syndrome is a genetic condition caused by a deletion of genes located on chromosome 11, often causing eye problems and increased risk of cancer in babies.