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Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
… Bacteria, Chromosome, Deoxyribonucleic Acid (DNA), Gene, Cloning, DNA Sequencing, Genetic Engineering Recombinant DNA …
Educational Resources
Fact sheets explaining complex concepts in genomics research to a non-scientific audience.
… Chromosome Abnormalities, Cloning, Comparative Genomics, Deoxyribonucleic Acid (DNA), …
Educational Resources
Yeast artificial chromosome (YAC) is a human-engineered DNA molecule used to clone DNA sequences in yeast cells.
News Release
Daniel Kastner, M.D., Ph.D., Scientific Director for the Intramural Research Program at the National Human Genome Research Institute (NHGRI) recognized for his pioneering work on the genomics of autoinflammatory diseases.
… when genomic infrastructure was still lacking, they used positional cloning to find the gene, an effort that took eight years and …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
Policies and Guidance
This page provides an overview of Resource Sharing Plans, a required document in most NIH funding applications. Most applicants for NIH funding must provide a Resource Sharing Plan (RSP) documenting plans for sharing resources that result from their federally funded work. NIH Policies that govern the sharing of resources include the NIH Model Organism Sharing Policy and the NIH Research Tools Policy.
… (e.g., animal models, antibodies, cell lines, clones and cloning tools, combinatorial chemistry and DNA libraries, …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
The Genomics Landscape
In the April 2021 issue of the Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D. talks about the NIH UNITE program's goal to end structural racism in biomedical research.
The Genomics Landscape
In the June 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D. details the upcoming appointment of acting NHGRI Deputy Director, Vence Bonham Jr., J.D. and what it means for the institute.
… personally involved in several such projects, including positional cloning of a fusion gene in leukemia, the identification of …
Staff
Dr. Raman Sood is an associate investigator in the Translational and Functional Genomics Branch and director of the Zebrafish Core at the National Human Genome Research Institute. ​
… research ranging from genome-wide association studies to positional cloning to functional genomic analyses using animal models. … E, Robbins CM, Moses T, Namkoong J, Chen S, and Trent JM. Cloning and characterization of a novel gene, SHPRH, encoding … Baxevanis A, Klingler K, Landes G, Trent J, and Carpten J. Cloning and characterization of 13 novel transcripts and the …