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Event
Several NIH Institutes, Offices and Centers are partnering to host a two-day virtual workshop on May 28-29, 2024, to further explore the recommendations from the National Academies of Sciences, Engineering and Medicine (NASEM) 2023 report, Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field, with regards to legacy genomic data. 
The Genomics Landscape
In May 4, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., details a report released by the National Academies of Science, Engineering, and Medicine, that provided a series of recommendations for using population descriptors in future genetics and genomics studies.
… scientific progress, the terms used to describe human populations have remained stuck in the past. Genetics and … reproducibility of research studies and ensure that all populations benefit from genomic advances. The scientific and …
News Release
Researchers at the National Institutes of Health (NIH) question advertisements by direct-to-consumer genetic ancestry kits that claim to know what it really means to be American Indian.
… … When Sara Hull, PhD. and Hina Walajahi traveled to Alaska in July of 2018 to give a talk on ethics and genetic … certain ancestry. So, a test that claims an individual has Native American ancestry, could be wrong. Hull soon … identity begins to fall apart.  A Haida house post at the Alaska Native Heritage Center in Anchorage, AK. The house …
News Release
NIH-backed African scientists are engaged in a global research endeavor to understand the genetic basis of disease in all populations.
… endeavor to understand the genetic basis of disease in all populations. But this can only be done by including populations that are the most genetically diverse. … A Global Research Endeavor Studies have shown that African populations contain the oldest and most diverse set of human …
News Release
NIH will fund grants totaling $38 million over five years to develop methods that will improve the way that polygenic risk scores can be used to predict disease in diverse communities.
… were developed using data from mostly European ancestry populations, are not effective when used in diverse populations. The new consortium, called PRIMED , will pool … that the scores accurately predict disease across diverse populations. Researchers have used available large-scale …
News Release
NIH researchers have sequenced the whole genome of a dog native to Sardinia, Italy, and discovered in it clues about the migration of humans to the area.
… have sequenced the whole genome of a dog that is native to the mountains of Sardinia, Italy, and discovered in … … NIH researchers have sequenced the whole genome of a dog native to Sardinia, Italy, and discovered in it clues about … … NIH researchers have sequenced the whole genome of a dog native to Sardinia, Italy, and discovered in it clues about …
News Release
NIH-funded research highlights need for diversity in study populations, creates a comprehensive genomic toolkit for scientists
… NIH-funded research highlights need for diversity in study populations, creates a comprehensive genomic toolkit for … data from 49,839 African-American, Hispanic/Latino, Asian, Native Hawaiian, Native American and people who identified as others and were …
Research at NHGRI
CRGGH facilitates understanding of the relationship between genetic variation and population differences in disease distribution to inform health disparities.
… patterns and determinants of common complex diseases in populations in the United States and around the world. … … dyslipidemia, and kidney diseases, in different human populations with particular attention to African Americans … the analysis of data generated in Africans and other populations.  Investigate how knowledge and understanding of …
News
To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.
… polygenic risk scores have not been effective for all populations, the researchers recalibrated these genetic tests … a more accurate assessment of disease risk across diverse populations. Genetic tests look at the small differences … many individuals with ancestry spanning two or more global populations. Strong representation of these individuals is …
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… cause common periodic fever have spread in Mediterranean populations over centuries, potentially protecting people … plague. … Researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory … have been positively selected for in Mediterranean populations over centuries. The findings were published in …